news
Optical imaging technique to detect tiny tumours
A method of imaging using longer wavelengths could mean that tiny tumours and clusters of cancer cells may be detected earlier than current methods allow...
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Drug Development
webinar
Phenotypic screening using iPSC-based human disease biology
18 February 2019 | By Tecan and Ncardia
Ncardia, will discuss the application of human iPSC-derived cell-based assays and high throughput screening for drug discovery and development.
news
Developing a blood test for pain measurement
A blood test to measure pain has been developed, and could potentially aid physicians with more accuracy in diagnosis and prescriptions...
news
Development of a gel for liver cell culture on microchips
Hydrogels could be used to build organs on chips to test potential medications, with the aim that they could potentially replace animal studies...
article
Hit-to-lead discovery at a nonprofit research institute
Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying and optimising compounds that target possible disease-driving…
news
Mavoglurant could improve eye gaze in fragile X patients
A first stage trial involving the experimental drug mavoglurant has shown early success in the treatment of gaze avoidance in fragile X syndrome patients...
news
Genetic study reveals possible new routes to treating osteoarthritis
Scientists discover new genes and biological pathways linked to osteoarthritis, which could help identify starting points for new medicines...
news
How gut bacteria affect the treatment of Parkinson’s disease
Researchers have investigated the ability of gut microbiota to influence the bioavailability of levodopa, a drug used in the treatment of Parkinson's...
article
Small molecules could have big benefits in the battle against cancers
Immunotherapy and targeted treatments, including targeted chemotherapy, continue to show great potential in cancer care. Future steps in their development will involve improving their ability to treat a wider range of cancers and a broader cross-section of the patient population, especially those for whom current treatments have shown limited efficacy...
article
Targeting innate immunity to treat disease: potential therapeutic applications
Despite being one of the more ancient aspects of immunity, therapeutic modulation of the innate immune system has rarely been attempted. Innate immunity is intrinsically linked to the generation of inflammation – necessary for signalling to the adaptive immune system but often self-perpetuating and over-exaggerated, leading to deleterious effects, including…
whitepaper
Application note: Transforming your bioanalysis operations – is a lack of insight slowing you down?
Many bioanalytical labs work with a crowded and siloed set of systems and processes. From part electronic to part paper-based workflows to standalone point-solutions, the result is a lack of insight into data and slower reporting and results handling.
whitepaper
Application note: Direct measurements of cellular metabolism for identification of mitochondrial drug targets
Drug target identification has a key role in the drug discovery value chain. A critical step in the development of pharmaceuticals is identifying the direct targets of potential drug candidates as well as distinguishing any secondary or off-target effects...
news
Freeze-dried vaccine may help eradicate polio
Researchers have developed a polio vaccine that doesn't require refrigeration, meaning it could someday be used all over the world...
news
Spined soldier bug can be used to develop new classes of antibiotics
Researchers have identified the mechanism by which thanatin attacks the way the outer membrane of Gram-negative bacteria is built...
webinar
High throughput screening for deep mining of antibody repertoires, Dr. Stefan Moese, Novartis, Switzerland
9 November 2018 | By Beckman Coulter
In this webinar you learn about a high throughput screening approach for mining of antibody repertoires in the context of biologics drug discovery.
