List view / Grid view

Disease research

news

Glioblastoma survival mechanism reveals new therapeutic target

12 December 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have provided insights into a mechanism of tumour survival in glioblastoma and demonstrated that inhibiting the process could enhance the effects of radiation therapy...

news

Chemists develop Washington Red dye for bio-imaging

11 December 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have created an injectable dye that illuminates molecules with near-infrared light...

news

New research heralds future drug discovery pathways for hyperaldosteronism

8 December 2017 | By Drug Target Review

A team of scientists in the United States has identified a mechanism that explains the development of hyperaldosteronism. These findings offer a potential path for drug discovery to treat the condition, which often leads to secondary hypertension.

article

Informatics In-Depth Focus 2017

8 December 2017 | By Drug Target Review

In this In-Depth Focus we look at using bioinformatics sequence similarities to optimise repurposing activities; informatics infrastructure in neglected disease research, and machine learning for accelerating drug discovery.

news

Scientists discover a small molecule that halts kidney disease progression

7 December 2017 | By Drug Target Review

A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.

news

Healthy mitochondria may prevent Alzheimer’s disease

7 December 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have provided a therapeutic approach to slow down the progression of neurodegeneration in Alzheimer's disease...

New Alzheimer’s animal model more closely mimics human disease

news

New Alzheimer’s animal model more closely mimics human disease

5 December 2017 | By Drug Target Review

Researchers have found that amyloid-? facilitates the interaction between the plaques and abnormal tau.

news

DNA sequencing demonstrates use for treatment of chronic kidney disease

5 December 2017 | By Drug Target Review

Results from a new study suggest that DNA sequencing could soon become part of the routine diagnostic examination for patients with chronic kidney disease.

Sperm RNA may serve as biomarkers of future health

news

Sperm RNA may serve as biomarkers of future health

4 December 2017 | By Drug Target Review

Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study.

news

Tumour cell biology reveals characteristic that causes metastasis

30 November 2017 | By Drug Target Review

A collaborative team of researchers in the US have uncovered characteristics of tumour cells that are linked to cancer metastasis.

news

Lung tumours communicate with bones to progress disease

30 November 2017 | By Drug Target Review

Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.

news

Scientists make key development in understanding type-2 diabetes mechanism

29 November 2017 | By Drug Target Review

Scientists at the University of Geneva (UNIGE) have deciphered the mechanisms that link obesity with type-2 diabetes at the cellular level, thus explaining the reasons behind an association that is already well known.

news

CXCL5 protein found to stimulate tumour growth in prostate cancer

24 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers identify a pathway that causes tumour acceleration in metastatic prostate cancer cells...

news

SBP scientists uncover mechanism for blood vessel regeneration

23 November 2017 | By Drug Target Review

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) has identified a signalling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels.

news

Engineering the gut microbiome may help treat Crohn’s disease

15 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have singled out a bacterial enzyme behind an imbalance in the gut microbiome linked to Crohn's disease...

Cookie	Type	Duration	Description
cookielawinfo-checkbox-advertising-targeting	persistent	1 year	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".
cookielawinfo-checkbox-analytics	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Analytics".
cookielawinfo-checkbox-necessary	persistent	1 year	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-performance	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Performance".
PHPSESSID	session	1 year	This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
viewed_cookie_policy	persistent	1 year	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
zmember_logged	session	1 year	This session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users.

Cookie	Type	Duration	Description
advanced_ads_browser_width	persistent	1 month	This cookie is set by Advanced Ads and measures the browser width.
advanced_ads_page_impressions	persistent	2 years	This cookie is set by Advanced Ads and measures the number of previous page impressions.
advanced_ads_pro_server_info	persistent	1 month	This cookie is set by Advanced Ads and sets geo-location, user role and user capabilities. It is used by cache busting in Advanced Ads Pro when the appropriate visitor conditions are used.
advanced_ads_pro_visitor_referrer	persistent	1 year	This cookie is set by Advanced Ads and sets the referrer URL.
bscookie	persistent	2 years	This cookie is a browser ID cookie set by LinkedIn share Buttons and ad tags.
IDE	persistent	2 years	This cookie is set by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
li_sugr	persistent	3 months	This cookie is set by LinkedIn and is used for tracking.
UserMatchHistory	persistent	1 month	This cookie is set by Linkedin and is used to track visitors on multiple websites, in order to present relevant advertisement based on the visitor's preferences.
VISITOR_INFO1_LIVE	persistent	5 months	This cookie is set by YouTube. Used to track the information of the embedded YouTube videos on a website.

Cookie	Type	Duration	Description
bcookie	persistent	2 years	This cookie is set by LinkedIn. The purpose of the cookie is to enable LinkedIn functionalities on the page.
GPS	persistent	30 minutes	This cookie is set by YouTube and registers a unique ID for tracking users based on their geographical location
lang	session	1 year	This cookie is set by LinkedIn and is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website.
lidc	persistent	1 day	This cookie is set by LinkedIn and used for routing.
lissc	persistent	11 months	This cookie is set by LinkedIn share Buttons and ad tags.
vuid	persistent	2 years	We embed videos from our official Vimeo channel. When you press play, Vimeo will drop third party cookies to enable the video to play and to see how long a viewer has watched the video. This cookie does not track individuals.
wow.anonymousId	persistent	2 years	This cookie is set by Spotler and tracks an anonymous visitor ID.
wow.schedule	persistent	20 minutes	This cookie is set by Spotler and enables it to track the Load Balance Session Queue.
wow.session	persistent	20 minutes	This cookie is set by Spotler to track the Internet Information Services (IIS) session state.
wow.utmvalues	persistent	20 minutes	This cookie is set by Spotler and stores the UTM values for the session. UTM values are specific text strings that are appended to URLs that allow Communigator to track the URLs and the UTM values when they get clicked on.
_ga	persistent	2 years	This cookie is set by Google Analytics and is used to calculate visitor, session, campaign data and keep track of site usage for the site's analytics report. It stores information anonymously and assign a randomly generated number to identify unique visitors.
_gat	persistent	1 minute	This cookies is set by Google Universal Analytics to throttle the request rate to limit the collection of data on high traffic sites.
_gid	persistent	1 day	This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. The data collected including the number visitors, the source where they have come from, and the pages visited in an anonymous form.

Cookie	Type	Duration	Description
cf_ob_info	persistent	1 minute	This cookie is set by Cloudflare content delivery network and, in conjunction with the cookie 'cf_use_ob', is used to determine whether it should continue serving “Always Online” until the cookie expires.
cf_use_ob	persistent	1 minute	This cookie is set by Cloudflare content delivery network and is used to determine whether it should continue serving “Always Online” until the cookie expires.
free_subscription_only	session	1 year	This session cookie is served by our membership/subscription system and controls which types of content you are able to access.
ls_smartpush	persistent	1 month	This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site.
one_signal_sdk_db	persistent	Until cleared	This cookie is set by OneSignal push notifications and is used for storing user preferences in connection with their notification permission status.
YSC	session	1 year	This cookie is set by Youtube and is used to track the views of embedded videos.

Recommended

Disease research