news Scientists halt breast cancer spread 9 February 2018 | By Drug Target Review Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.
news CRISPR method efficiently corrects DMD defect in heart tissue 8 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of mutations that cause DMD...
news Nicotinamide riboside shows cognitive benefits in Alzheimer’s disease 7 February 2018 | By Dr Zara Kassam (Drug Target Review) A form of vitamin B3 has been found to prevent neurological damage and improve cognitive and physical function in a new mouse model of Alzheimer’s disease...
news Study indicates holistic nature of Alzheimer’s disease (AD) progression 7 February 2018 | By Drug Target Review A collaboration of scientists in the United States has identified a distinct association between inflammation biomarkers in blood plasma and cerebrospinal fluid (CSF), and markers of Alzheimer’s disease (AD).
news Immune system found to protect against MRSA infections 7 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus...
news Searching for targeted treatments for inflammatory diseases 7 February 2018 | By Drug Target Review Scientists have identified identified key regulators that are essential for controlling the inflammatory response in Crohn’s disease and multiple sclerosis.
news Precise genetic cause of rare hypertension syndrome is discovered 6 February 2018 | By Drug Target Review Scientists at the Berlin Institute of Health have discovered how mutations in a new disease gene CLCN2 cause the unusual inherited form of high blood pressure: Familial hyperaldosteronism type II.
news Reprogrammed brain cells exhibit symptoms of Huntington’s disease 6 February 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have transformed skin cells from patients with Huntington's disease into the type of brain cell affected by the disorder...
news Chondroitin sulphate nets hold promise for heart failure treatments 2 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers discover molecular nets inside heart muscles which hold promise for new heart failure treatment...
news Scientists discover new epigenetic cause of cblC that shifts rare disease paradigm 1 February 2018 | By Drug Target Review Researchers in France and Canada have discovered an epigenetic alteration of a vitamin B12 gene – MMACHC – that has significant implications for our understanding of cblC and other rare diseases.
news Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype 31 January 2018 | By Drug Target Review A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.
news Novel curative gene therapy treatment for pulmonary fibrosis in mice 30 January 2018 | By Drug Target Review Researchers in Spain have developed a method of gene therapy that cures pulmonary fibrosis in mice by lengthening telomeres – the protective protein sections at the end of chromosomes.
news ZNF274 deletion reverses Prader-Willi syndrome 29 January 2018 | By Dr Zara Kassam (Drug Target Review) Reversing the imprinting that causes Prader-Willi syndrome gives hope that epigenetic diseases can be cured...
news Systemic clearing of senescent astrocytes presents new therapeutic avenue for Parkinson’s disease 25 January 2018 | By Drug Target Review Researchers illuminate a new focal area for Parkinson’s disease therapy after demonstrating the beneficial effects of systemic clearing of senescent astrocytes.
news Researchers uncover the origins of leprosy and reason for its drug resistance 25 January 2018 | By Drug Target Review Scientists in Switzerland have developed the tools to sequence genes from the leprosy bacterium, Mycobacterium leprae, revealing information about its origins and reasons behind its resistance to drugs.
