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A1C proteins associated with diabetic complications and heart disease

12 March 2018 | By Dr Zara Kassam (Drug Target Review)

Protein pathways that are closely linked to changes in both triglyceride and haemoglobin A1c levels in diabetic patients have been identified...

news

CRISPR-based system identifies drug targets in AML

12 March 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have discovered a way to rein in an overactive protein that drives some aggressive leukaemias...

news

CRISPR/Cas9 technique suppresses malaria infection in mosquitos

9 March 2018 | By Dr Zara Kassam (Drug Target Review)

Genome editing could enable new strategies to prevent malaria transmission to humans...

news

EGFL7 protein provides a new treatment approach for MS

7 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that the EGFL7 protein inhibits the migration of immune cells into the brain...

news

Splicing-variant detection method identifies biomarkers for HCC

6 March 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers report a method for identifying splicing-based biomarkers for hepatocellular carcinoma....

news

Scientists find that dectin-1 receptor protects against allergies

2 March 2018 | By Drug Target Review

Contrary to previous notions that the receptor dectin-1 causes allergic reactions, new research from the John Hopkins Bloomberg School of Public Health has found that it actually prevents this response, indicating new targets for allergy and asthma drugs.

news

Researchers evaluate tau phosphorylation related targets for Alzheimer’s research

1 March 2018 | By Drug Target Review

Scientists in Moscow have extended the reach of QSP modelling by applying it to tau phosphorylation to better understand Alzheimer’s disease (AD) progression.

news

Tempol provides a potential treatment for Chuvash polycythemia

28 February 2018 | By Dr Zara Kassam (Drug Target Review)

A study in mice suggests that experimental drug may be effective against mountain sickness and other polycythemias...

news

Neural stem cell treatment may offer relief for MS

27 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have shown that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by MS...

news

Five genetic changes linked to pancreatic cancer risk

27 February 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer...

news

CRISPR/Cas9 variant holds promise for Huntington’s disease treatment

26 February 2018 | By Dr Zara Kassam (Drug Target Review)

Improvements to gene-editing techniques hold promise for inactivating the defective gene responsible for this as-yet incurable disease...

news

Mouse study demonstrates that gut microbes protect against sepsis

23 February 2018 | By Drug Target Review

A recent study at the University of Pennsylvania has identified that introducing particular microflora to the blood of mice increases immunoglobin A (IgA) levels, which appears to aid survival against sepsis.

news

Local environment plays key role in breast cancer progression

22 February 2018 | By Dr Zara Kassam (Drug Target Review)

While studying the complex correlation between tissue stiffness and breast cancer development, researchers found that cancer cells tend to become more aggressive when the surrounding tissue stiffens...

news

The spreading mechanism of malaria parasites provides new drug target

22 February 2018 | By Drug Target Review

A team of researchers in the UK have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, thus offering potential new treatment targets.

news

STEEL gene senses inadequate blood flow in microscopic blood vessels

22 February 2018 | By Dr Zara Kassam (Drug Target Review)

A new study has found that a newly discovered gene helps grow blood vessels when it senses inadequate blood flow to tissues...

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