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Disease research

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EBV protein can ‘switch on’ risk genes for autoimmune diseases

17 April 2018 | By Drug Target Review

EBV may trigger some cases of lupus, say NIH-supported researchers...

news

Nanoparticles shown to be effective in treating NSCLC

16 April 2018 | By Dr Zara Kassam (Drug Target Review)

Non-small cell lung cancer Nanoparticles pass the next stage of development in preclinical tests...

news

Disrupting macrophage action aids melanoma immunotherapy success

13 April 2018 | By Drug Target Review

Scientists in Switzerland have uncovered a potential means of increasing effective treatment of melanomas with immunotherapy, by disrupting the action of macrophages.

news

New class of drugs could help tackle treatment-resistant cancers

12 April 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...

news

BNIP1 identified as a risk gene for ALS

10 April 2018 | By Dr Zara Kassam (Drug Target Review)

Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...

article

How the study of lipidomics is benefiting from recent advances in mass spectrometry

10 April 2018 | By Cristina Legido-Quigley (Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen)

There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.

news

Macular degeneration linked to ageing immune cells

9 April 2018 | By Dr Zara Kassam (Drug Target Review)

Older cells promote inflammation, abnormal blood vessel growth that can lead to blindness...

news

Researchers uncover protective role of oestrogen against type-2 diabetes

9 April 2018 | By Drug Target Review

Scientists in Switzerland reveal the mechanisms behind the protective role of oestrogen against developing type 2 diabetes.

news

New method allows scientists to watch brain cells interacting in real time

6 April 2018 | By Drug Target Review

Findings could deepen understanding of neurological disorders...

news

Study develops compound that activates tumour-fighting iNKT cells

6 April 2018 | By Drug Target Review

Researchers have discovered a significant new compound that helps to mobilise a type of T cell – invariant natural killer T (iNKT) cells – in the fight against disease.

news

Fragile X imaging study reveals differences in infant brains

5 April 2018 | By Dr Zara Kassam (Drug Target Review)

For the first time, researchers have used MRIs to show that babies with the neurodevelopmental condition fragile X syndrome had less-developed white matter compared to infants that did not develop the condition...

news

SAMHD1 enzyme may block HIV disease progression

4 April 2018 | By Dr Zara Kassam (Drug Target Review)

One way to fight diseases including HIV infection and autoimmune disorders could involve changing how a naturally occurring enzyme called SAMHD1 works...

news

Animal model of Huntington’s offers advantages for testing treatments

2 April 2018 | By Dr Zara Kassam (Drug Target Review)

Using genetic engineering technology, a team of scientists have established an animal model of Huntington's disease...

news

Nicotinic receptor research paves way for targeted dementia therapy

28 March 2018 | By Dr Zara Kassam (Drug Target Review)

A new study which identifies how acetylcholine impacts learning and memory by acting at different receptors could prove significant in the drive to develop more targeted and effective therapies for dementia...

news

I-BET-762 may stop cancer-causing gene in its tracks

28 March 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer...

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