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RNA-modifying tool corrects genetic diseases

31 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a small-molecule-based tool that acts on RNA to selectively delete certain gene products...

Changes to specific MicroRNA involved in development of Lou Gehrig’s disease

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Changes to specific MicroRNA involved in development of Lou Gehrig’s disease

31 May 2018 | By Drug Target Review

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS).

news

IL-25 molecule linked to nasal polyps

30 May 2018 | By Drug Target Review

Study could lead to the development of new treatments for common sinus conditions...

news

Gut microbiome can control anti-tumour immune function in liver

29 May 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have found a connection between bacteria in the gut and antitumor immune responses in the liver...

news

Researchers in Spain elucidate complete epigenome for leukaemia

25 May 2018 | By Drug Target Review

A team of researchers in Spain show for the first time the complete epigenome of chronic lymphocytic leukaemia, the most common type of leukaemia.

news

Immune processes offer insights into triple-negative breast cancer

25 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered the process that allows immune suppressor cells to develop, suggesting a potential new way to bolster immunotherapy treatment...

news

Three new genes linked to Alzheimer’s identified

24 May 2018 | By Drug Target Review

An international research team has identified three new genes linked to the risk of Alzheimer’s disease...

news

Scientists reveal model that estimates lifetime risk of developing Alzheimer’s dementia

23 May 2018 | By Drug Target Review

The Alzheimer’s Association have published a study wherein a model estimates the lifetime risk of an individual developing Alzheimer’s disease dementia. The risk varies with such factors as age and gender, and crucially takes account of preclinical biological changes.

news

Link between TB and Parkinson’s disease identified

23 May 2018 | By Dr Zara Kassam (Drug Target Review)

The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...

news

Cell types underlying schizophrenia identified

23 May 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...

news

Diabetes researchers find switch for fatty liver disease

18 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have identified a key in the road for the way the liver deals with carbohydrates, fats and protein...

news

Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation

18 May 2018 | By Charles River Laboratories

Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.

news

IL1RAP protein boosts multiple oncogenic pathways in AML

18 May 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...

news

mEAK-7 gene could suggest path towards cancer therapies

16 May 2018 | By Drug Target Review

Researchers have found mEAK-7 regulates the molecular process that dictates cell growth and human development...

news

A link between Huntington’s disease and rheumatoid arthritis identified

15 May 2018 | By Dr Zara Kassam (Drug Target Review)

Epigenomic analyses may lead to other unexpected findings and novel therapeutic drug targets for many diseases

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