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Injected VEGF-C could prevent heart failure
Vascular Endothelial Growth Factor C (VEGF-C) could aid the repair and recovery of hearts after a heart attack, by enabling immune cells to clear dead and dying cells...
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3D map of CVD genetic interactions could aid future treatments
A 3D map of genetic interactions in CVD could aid researchers investigating future treatments for heat attacks, heart failure and heart rhythm disorders.
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Study pinpoints the ‘Big Bang’ of tau-induced Alzheimer’s neurodegeneration
Scientists in the U.S. have identified what they believe to be the genesis of Alzheimer's disease – the precise point at which a healthy tau protein becomes toxic but has not yet formed deadly tangles in the brain. The finding opens up numerous avenues for treatment research.
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PNA gene editing technique cures beta-thalassemia in utero
Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model...
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How does Parkinson’s disease develop?
Study raises doubts on a previous theory of Parkinson’s disease...
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Experimental drug stops Parkinson’s disease progression in mice
Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...
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New cancer immunotherapy shows promise in early tests
Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...
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C6 gene unlocks mysteries to our immunity
Researchers have identified a new gene that plays a critical role in regulating the body's immune response to infection and disease...
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Computational models provide genetic insight into atherosclerosis
Researchers find a gene in artery wall activated by lipids associated with coronary artery disease...
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TRAF7 gene mutations associated with multisystem disorders
A team of researchers have identified four different mutations in the gene TRAF7...
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Scientists uncover the mechanism by which cancer cells resist ageing
Scientists in the U.S. have found that human lung cancer cells resist dying by controlling parts of the ageing process. The discovery could help us better understand ageing and eventually lead to new treatments for cancer.
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Genes linking Alzheimer’s and Down syndrome discovered
Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...
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NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease
Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.
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Human immune ‘trigger’ map paves way for better treatments
A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders...
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Gene signature holds promise for early detection of active TB
A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.
