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Disease research

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Injected VEGF-C could prevent heart failure

12 July 2018 | By Drug Target Review

Vascular Endothelial Growth Factor C (VEGF-C) could aid the repair and recovery of hearts after a heart attack, by enabling immune cells to clear dead and dying cells...

news

3D map of CVD genetic interactions could aid future treatments

12 July 2018 | By Drug Target Review

A 3D map of genetic interactions in CVD could aid researchers investigating future treatments for heat attacks, heart failure and heart rhythm disorders.

news

Study pinpoints the ‘Big Bang’ of tau-induced Alzheimer’s neurodegeneration

11 July 2018 | By Drug Target Review

Scientists in the U.S. have identified what they believe to be the genesis of Alzheimer's disease – the precise point at which a healthy tau protein becomes toxic but has not yet formed deadly tangles in the brain. The finding opens up numerous avenues for treatment research.

news

PNA gene editing technique cures beta-thalassemia in utero

10 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model...

news

How does Parkinson’s disease develop?

6 July 2018 | By Dr Zara Kassam (Drug Target Review)

Study raises doubts on a previous theory of Parkinson’s disease...

news

Experimental drug stops Parkinson’s disease progression in mice

5 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...

news

New cancer immunotherapy shows promise in early tests

3 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...

news

C6 gene unlocks mysteries to our immunity

2 July 2018 | By Drug Target Review

Researchers have identified a new gene that plays a critical role in regulating the body's immune response to infection and disease...

news

Computational models provide genetic insight into atherosclerosis

29 June 2018 | By Drug Target Review

Researchers find a gene in artery wall activated by lipids associated with coronary artery disease...

news

TRAF7 gene mutations associated with multisystem disorders

29 June 2018 | By Drug Target Review

A team of researchers have identified four different mutations in the gene TRAF7...

news

Scientists uncover the mechanism by which cancer cells resist ageing

28 June 2018 | By Drug Target Review

Scientists in the U.S. have found that human lung cancer cells resist dying by controlling parts of the ageing process. The discovery could help us better understand ageing and eventually lead to new treatments for cancer.

news

Genes linking Alzheimer’s and Down syndrome discovered

26 June 2018 | By Drug Target Review

Scientists are a step closer to understanding which genes are responsible for early-onset Alzheimer's disease in people with Down syndrome...

NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease

news

NIH-funded study finds new evidence that viruses may play a role in Alzheimer’s disease

25 June 2018 | By Drug Target Review

Analysis of large data sets from post-mortem brain samples of people with and without Alzheimer's disease has revealed new evidence that viral species, particularly herpesviruses, may have a role in Alzheimer’s disease biology.

news

Human immune ‘trigger’ map paves way for better treatments

21 June 2018 | By Drug Target Review

A discovery about how human cells are 'triggered' to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders...

news

Gene signature holds promise for early detection of active TB

20 June 2018 | By Drug Target Review

A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.

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