news Monoclonal antibodies produced by new cell lines hope to improve drugs 1 August 2018 | By Drug Target Review Many biopharmaceutical companies look to produce biosimilars soon, since the patents on the original mAb expire over the next few years...
news Research into cellular signalling mechanisms may lead to new treatments 31 July 2018 | By Drug Target Review Wnt moves to specific areas of the cell membrane, interacting with a receptor known as Ror2, and inducing the formation of a cytoneme...
news Novel antibiotics can be found on common weeds 31 July 2018 | By Drug Target Review The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...
news IKZF1 gene could improve cancer immunotherapy 31 July 2018 | By Dr Zara Kassam (Drug Target Review) A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy...
news CMPK2 inhibitor could lesson symptoms of common illnesses 27 July 2018 | By Drug Target Review CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
news UBR5 protein may reduce neurodegeneration in Huntington’s disease 27 July 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease...
news New drug for ALS ready for clinical trials 26 July 2018 | By Drug Target Review Previous studies have suggested that a gene therapy drug may be used to treat ALS...
news BCX7353 shows hope for hereditary angioedema 26 July 2018 | By Dr Zara Kassam (Drug Target Review) A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...
news Blood test predicts the best treatment for prostrate cancer 26 July 2018 | By Drug Target Review The study showed that patients testing positive for AR-V7 responded better to taxane-based chemotherapy and negative to hormone-targeted therapy...
news Researchers identify new arthritis severity gene 26 July 2018 | By Dr Zara Kassam (Drug Target Review) A new gene associated with disease severity in models of rheumatoid arthritis has been identified by...
news Study suggests viral connection to Alzheimer’s disease 25 July 2018 | By Drug Target Review A first-of-its-kind study implicates another culprit in the path to Alzheimer's disease: the presence of viruses in the brain...
news Promising drug targets for t-cell lymphoblastic leukaemia 25 July 2018 | By Drug Target Review Silencing the gene behind the production of HSP90, a target in the HSF1 pathway, effectively kills leukaemia cells, without affecting healthy cells...
article Adapting drug discovery to Artificial Intelligence 25 July 2018 | By Ami S Lakdawala (GSK's In-silico drug discovery unit), George Okafo (GSK's In-silico drug discovery unit), John Baldoni (GSK's In-silico drug discovery unit), Michael Palovich (GSK's In-silico drug discovery unit), Tobias Sikosek (GSK's In-silico drug discovery unit), Vishal Sahni (GSK's In-silico drug discovery unit) Drug discovery has always been challenging; today, more so than ever. While there has been success in addressing many diseases, others remain intractable...
news How cannabis and cannabis-based drugs can harm your brain 24 July 2018 | By Dr Zara Kassam (Drug Target Review) Long-term use of either cannabis or cannabis-based drugs impairs memory...
news Recessive disorder impairing eyesight has been discovered 24 July 2018 | By Drug Target Review Blindness in children has been linked to a recessive genetic disorder caused by the MARK3 gene...
