news Genes increasing the risk of triple-negative breast cancer identified 8 August 2018 | By Drug Target Review Germ line genetic testing analyses blood samples and evaluates inherited genetic changes that increase the risk of certain cancers in an individual...
news Reducing NOVA1 helps prevent tumour growth in lung cancer 8 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a gene that when inhibited, reduced human non-small cell lung cancer tumours from growing...
news ‘Drug cocktails’ could strengthen targeted cancer therapies 7 August 2018 | By Drug Target Review "Targeted therapies have revolutionised cancer treatment by targeting fewer components within a human cell, thereby promising better efficacy..."
news New drugs targeting gut microbes may reduce the risk of cardiovascular disease 7 August 2018 | By Drug Target Review The new class of drugs are mechanism-based inhibitors which potentially interrupt the gut microbial pathway that produces TMAO...
news CRISPR-Cas9 used to correct sickle cell–causing mutation 7 August 2018 | By Dr Zara Kassam (Drug Target Review) Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells...
news Novel PET imaging could guide therapy for type 1 diabetes 6 August 2018 | By Drug Target Review Since beta cells and neurological tissues have common receptors, researchers screened brain radioligands for their ability to identify beta cells...
news pH imbalance in astrocytes may lead to Alzheimer’s disease 6 August 2018 | By Drug Target Review The researchers found that 10 of the 100 most frequently down-regulated genes were connected with proton flow in the cell...
news BDNF protein could be key to preserving heart function in DMD 6 August 2018 | By Drug Target Review A protein known to drive nerve cell survival in the brain and spinal cord may also protect failing hearts in children and young adults with DMD...
news Aortic plaques may contribute to liver disease progression 3 August 2018 | By Drug Target Review Aortic atherosclerotic plaque inflammation may contribute to the progression of non-alcoholic fatty liver disease to liver fibrosis...
news miR-132 offers hope for novel Alzheimer’s treatments 3 August 2018 | By Dr Zara Kassam (Drug Target Review) The study of neuroprotective microRNAs like miR-132 may lead to new avenues for treating Alzheimer's disease and other tau pathologies...
news New stem cell model to test treatments for neurodegenerative disorders 2 August 2018 | By Drug Target Review The team found that astrocytes inhibit growth of precursor cells that become myelin, and speed up the neural network in the brain...
news Potential peptide drug could treat liver cancer effectively 2 August 2018 | By Drug Target Review Researchers have discovered that FFW and Sorafenib used together could reduce the growth of Sorafenib resistant hepatocellular carcinoma tumours...
news D-PDMP reverses hair loss and skin damage linked to fatty diet 2 August 2018 | By Dr Zara Kassam (Drug Target Review) In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...
news Computer simulations predict the spread of HIV 2 August 2018 | By Dr Zara Kassam (Drug Target Review) Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...
news Is acidity the weakness of cancer cells? 1 August 2018 | By Drug Target Review Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...
