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Disease research

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Parasitic worm study predicts potential drug targets and drugs

6 November 2018 | By Iqra Farooq (Drug Target Review)

The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...

news

Potential of gene therapy for neurological disorders

6 November 2018 | By Iqra Farooq (Drug Target Review)

Gene therapy could be effective in numerous neurological conditions and could transform the lives of patients with these incurable diseases...

news

NGLY1 protein identified as potential target for melanoma treatment

6 November 2018 | By Drug Target Review

Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.

news

Tethered antibodies may prevent influenza virus infections

6 November 2018 | By Drug Target Review

Investigational therapeutic candidate made with four antibodies tethered together shows promise against influenza A and B...

news

Stem cell therapy with biodegradable scaffold

5 November 2018 | By Drug Target Review

A biodegradable scaffold used to transplant stem cells and deliver drugs, could help in the treatment of brain diseases...

news

Charles River to present collaborative methods at Neuroscience 2018

5 November 2018 | By Charles River Laboratories

Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...

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Biomarkers may predict Zika-related birth defects

5 November 2018 | By Drug Target Review

Researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus...

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Image of serotonin activating its receptor for the first time

2 November 2018 | By Drug Target Review

Researchers have managed to image serotonin activating its receptor for the first time using the cutting edge technology, cryo-electron microscopy...

news

MDM2 inhibitors as a possible treatment for uveitis

2 November 2018 | By Iqra Farooq (Drug Target Review)

MDM2 inhibitors could be used as a treatment for uveitis, a disease affecting the middle layer of the eye, causing inflammation and redness...

news

Antibacterial compounds focusing on LsrK kinase

1 November 2018 | By Drug Target Review

Researchers at the University of Eastern Finland have developed antibacterial compounds based on the action of LsrK kinase...

news

Biomarker discovered for heart failure with preserved ejection fraction

1 November 2018 | By Drug Target Review

A biomarker has been discovered for the most common type of heart failure - heart failure with preserved ejection fraction...

news

Biomarkers to detect and prevent liver cancer

31 October 2018 | By Iqra Farooq (Drug Target Review)

An increase in the expression of sugar-burning 'glycolytic' enzymes in precancerous cirrhotic livers has been identified and could be used as a biomarker...

news

Droplet Digital PCR detects and quantifies cancer mutation

31 October 2018 | By Drug Target Review

Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...

news

Chromatin study unearths link between DNA-protein binding and cancer

31 October 2018 | By Drug Target Review

A team of scientists led by Stanford University School of Medicine has identified a link between how proteins bind to our DNA and how cancer develops. This finding may allow researchers to predict cancer pathways and long-term patient outcomes.

news

Water as a biomarker against cancer?

30 October 2018 | By Iqra Farooq (Drug Target Review)

The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...

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