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Disease research

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Insights into molecular processes using isolated systems

22 November 2018 | By Drug Target Review

Using 2D isolated systems, scientists have developed a method of looking at microscopic molecular interactions, which may be beneficial in drug discovery...

news

Nanopore detection of single flu viruses to control influenza outbreaks

22 November 2018 | By Drug Target Review

Osaka University researchers have developed a method using single-particle nanopore sensors and AI to detect single influenza virions...

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Stopping cancer cells in their tumour ‘highways’

21 November 2018 | By Drug Target Review

Using controlled network microenvironments, tumour cells were prevented from travelling, which could prevent spread of the cancer throughout the body...

news

War On Cancer 2018: targeted therapies in oncology

21 November 2018 | By Iqra Farooq (Drug Target Review)

War On Cancer 2018 discussed how cancer treatments have evolved over the last few decades, and looked at the future of cancer therapies...

news

New information on the pathological mechanisms of Alzheimer’s disease

21 November 2018 | By Drug Target Review

Researchers have indicated that the accumulation of pathological tau triggers a safety valve mechanism in the otherwise well-regulated cell membranes...

news

Majority of HIV persistence during ART due to infected cell proliferation

20 November 2018 | By Drug Target Review

Study confirms biological mechanism responsible for latent HIV reservoirs; suggests strategies for a functional HIV cure...

news

Muscular paralysis progression could be reduced using tamoxifen

20 November 2018 | By Drug Target Review

Currently used for breast cancer, tamoxifen could be useful in preventing the progression of myotubular myopathy, a severe genetic disease...

news

Inflammation inhibitor could be used to treat sepsis

19 November 2018 | By Drug Target Review

An inhibitor that stops the action of OGG1 signals, could potentially be used as a treatment for life-threatening Acute Respiratory Distress Syndrome...

news

PCSK9 inhibitors to treat high cholesterol

16 November 2018 | By Drug Target Review

Low-density lipoprotein cholesterol could be treated by using synthetic DNA-encoded monoclonal antibodies to inhibit PCSK9...

news

Inhibiting inflammation by blocking release of TNF alpha

16 November 2018 | By Drug Target Review

Researchers at Karolinska Institutet collaborated with other researchers to develop a compound that prevents inflammation by blocking release of TNF alpha...

news

Drug candidate offers hope of vocal improvement for ADNP syndrome

16 November 2018 | By Drug Target Review

Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.

news

Using anti-malaria drugs to slow tumour growth

15 November 2018 | By Drug Target Review

Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...

news

Precision neuroengineering reproduces brain-like functions in vitro

15 November 2018 | By Drug Target Review

Using precision engineering, researchers form Japan and Spain have collaborated to show brain-like functions in vitro to advance medical research...

news

Immune cell enzyme protects against tuberculosis

14 November 2018 | By Drug Target Review

Using lung tissue from humans and mouse models, researchers have found that HO-1 controls inflammation and protects against tuberculosis...

news

Combination of imaging techniques views retina in unprecedented detail

14 November 2018 | By Drug Target Review

Using two imaging techniques, adaptive optics and angiography, researchers have been able to view the retina in more detail than ever seen before...

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Disease research