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Protection against Mayaro virus using engineered DNA vaccine
An engineered DNA vaccine that induces a robust and specific immune response against the disease, also provides complete protection...
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Disease research
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Hit-to-lead discovery at a nonprofit research institute
Small molecule drug discovery has long been the domain of pharmaceutical companies, and that’s not likely to change anytime soon. But there’s a cadre of universities and nonprofit research institutes that have embraced drug development at its earliest stages, in some cases identifying and optimising compounds that target possible disease-driving…
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The role of immune cells in metastasis
Specific immune cells, such as neutrophils, have been found to aid the progression of cancers, promoting metastasis in tumours...
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Treatment could prevents and treat Chlamydia
The development of a treatment that prevents and treats Chlamydia uses nanotechnology, and could change the way the disease is treated...
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Key function of specialised cells in peripheral nerve repair
The interaction between macrophages and Schwann cells could be vital in maintaining the repair process, without which could impair nerve function...
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Genetic sequence can predict protein production efficiency
Protein produced in a cell is crucial to maintaining the function of the organism, and this function is important to understand numerous human diseases...
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Mucus could be key to treating colon and airway diseases
The action of proteins that control mucus production could suggest clues to treating colon and airway conditions such as asthma or Crohn's disease...
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The path of metallodrugs in breast cancer cells
The path a metallodrug uses to target and kill cancer cells could be used to design drugs to target triple-negative breast cancer...
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Clusterin linked to both cardiac and metabolic diseases
The protein clusterin has been linked to different cardiometabolic syndrome risks, with researchers asking whether it could be a therapeutic target...
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Combination therapy may halt the progression of neuroblastoma in children
Researchers have uncovered a crucial link between polyamines and MYCN, revealing that the polyamine pathway is entirely regulated by the MYCN oncogene...
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How can the development of brain stem cells into neurons cause cancer?
The development of a brain stem cell into a neuron often occurs without problems, but there are times when it can transform into cancer...
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Immune regulators respond to parasite infections
The master regulator that maintains a healthy gut and limits damage by parasitic whipworms has been identified as the interleukin 10 receptor...
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Medical cannabis relieves symptoms in children with autism
Researchers have reported that medical cannabis appears to be a well-tolerated, safe and effective option to relieve symptoms in autism spectrum disorders...
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Exploring the genome using transcription factors
Using transcription factors to explore and understand the genome could lead to the understanding of gene expression patterns...
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Identifying the biomedical potential of bivalves
Shellfish, such as oysters, could help to revolutionise human health research by providing insights in cancer therapies and bacterial immunity...
