news Human tuberculosis blood signal replicated in mice 24 March 2020 | By Rachael Harper (Drug Target Review) More research into tuberculosis is now possible with the development of an optimisied mouse model that exhibits the same blood immune response to Mycobacterium tuberculosis infection as humans.
news Chronic use of heart disease medications may increase the risk of severe COVID-19 24 March 2020 | By Hannah Balfour (Drug Target Review) A researcher has revealed that angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARBs) may increase the risk of severe lung complications in COVID-19.
news UK Consortium to monitor spread and behaviour of coronavirus 24 March 2020 | By Hannah Balfour (Drug Target Review) The UK government has invested £20 million into the COVID-19 Genomics UK Consortium, which will use whole genome sequencing to inform infection control measures and therapeutic developments.
article Antibodies In-Depth Focus 2020 24 March 2020 | By Drug Target Review This In-Depth Focus includes articles on antibodies as a treatment for COVID-19, the importance of understanding every aspect of an ADC and the potential of antibodies as a targeted cancer therapeutic.
news COVID-19 research hub: promoting scientific collaboration 24 March 2020 | By Drug Target Review Drug Target Review has created a COVID-19 research hub with forum space for discussions and a place to share your research - plus all of our articles and news.
news High-speed microscope can capture brain signals and calcium concentrations 23 March 2020 | By Hannah Balfour (Drug Target Review) The novel technology allows researchers to create three-dimensional images of signal propagation and calcium concentration changes in the neocortex of live mice.
news Study shows how skin cells change when preparing to heal wounds 23 March 2020 | By Hannah Balfour (Drug Target Review) The researchers hope their study into how cellular heterogeneity changes as the skin heals wounds will allow further research into pathological conditions that cause poor wound healing.
news Understanding of COVID-19 infections in children will aid treatment development, say researchers 20 March 2020 | By Victoria Rees (Drug Target Review) A statement from scientists has highlighted that improving the understanding of COVID-19 infections in children will help researchers to develop better treatments.
news New cancer treatment regimens could be identified with novel technology 20 March 2020 | By Rachael Harper (Drug Target Review) A new technology called mass cytometry, or CyTOF, is providing new insights into a range of key proteins in blood cancer cells.
news Developing a COVID-19 testing kit using RNA detection 20 March 2020 | By Hannah Balfour (Drug Target Review) The developers of an RNA imaging technology are using it to create a COVID-19 coronavirus testing kit, able to recognise the viral genome.
news Technique for 2D printing of cells developed by researchers 19 March 2020 | By Victoria Rees (Drug Target Review) A study has demonstrated the success of a 2D printing method to create cell arrays that reflect the body's natural environment, allowing researchers to study stem cell differentiation.
article Where could bioengineering and technological advances take drug discovery? 19 March 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores the findings of a recent review of molecular, cellular, multi-cellular and tissue engineering and modelling technologies for drug design.
news Ion channel ball-and-chain mechanism imaged after decades of attempts 19 March 2020 | By Hannah Balfour (Drug Target Review) Scientists have imaged the ball-and-chain mechanism using cryogenic electron microscopy and hope their work could be applied in the design of novel therapeutics.
news CRISPR RNA-targeted genetic screen could be used for COVID-19 therapy 18 March 2020 | By Hannah Balfour (Drug Target Review) A new Cas13 RNA screen has been used to establish guide RNAs for the COVID-19 coronavirus and human RNA segments which could be used in vaccines, therapeutics and diagnostics.
news Mapping the immune response to COVID-19 17 March 2020 | By Hannah Balfour (Drug Target Review) Researchers reveal that a broad range of immune cells react to COVID-19 and aid recovery, findings which could inform the development of a potential vaccine.
