news Protective immunity to SARS-CoV-2 shown in non-human primates 21 May 2020 | By Hannah Balfour (Drug Target Review) Macaques were protected against SARS-CoV-2 infection both after an initial infection and vaccination with a prototype vaccine, researchers suggest humans could respond similarly.
news Human enzymes could be driving COVID-19 evolution, suggest researchers 21 May 2020 | By Hannah Balfour (Drug Target Review) Post-infection genome editing could be the cause of mutations in the SARS-CoV-2 virus responsible for the COVID-19 pandemic, driving its evolution.
news Analysis of immune response to SARS-CoV-2 gives hope for COVID-19 vaccines 19 May 2020 | By Victoria Rees (Drug Target Review) A detailed analysis of the body's immune response to COVID-19 has revealed that it can recognise SARS-CoV-2 in many ways, meaning vaccines can be used to stop the spread of the virus.
news Novel microfluidic and sequencing method enables epigenetic studies 19 May 2020 | By Victoria Rees (Drug Target Review) A new microfluidic technology has been developed which can profile histone modifications with as few as 100 cells per assay.
news Study finds coronaviruses do not readily induce cross-protective antibody responses 19 May 2020 | By Victoria Rees (Drug Target Review) Researchers have found that antibodies produced in response to SARS and COVID-19 are cross-reactive, but not cross protective in cells and mice.
news Lipid mediators suggested as potential COVID-19 inflammation treatment 18 May 2020 | By Victoria Rees (Drug Target Review) A new article has outlined the body's inflammatory response to COVID-19 infection, saying that lipid mediators derived from omega-3 fatty acids could prevent life-threatening inflammation.
news Scientists stress need for research into COVID-19 symptom treatment 15 May 2020 | By Victoria Rees (Drug Target Review) In a new article, researchers highlight the need for treatments to combat the potentially lethal overreaction of the immune system in the progression of COVID-19.
news Researchers observe how SARS-CoV-2 changes human cells after infection, revealing drug targets 15 May 2020 | By Victoria Rees (Drug Target Review) Using mass spectrometry, researchers have shown how human cells are changed by infection from SARS-CoV-2, allowing the team to identify drug targets to prevent viral reproduction.
news Researchers find TMPRSS2 and TMPRSS4 enable SARS-CoV-2 infection of digestive system 14 May 2020 | By Victoria Rees (Drug Target Review) A group of researchers has found that SARS-CoV-2 may not spread by faecal-to-oral transmission, but is able to infect the gastrointestinal tract via the TMPRSS2 and TMPRSS4 enzymes.
news Results from first epigenetic study in 3D human cancer cells published 14 May 2020 | By Victoria Rees (Drug Target Review) A new paper describes the first full study of the epigenetics of human tumour organoids, suggesting this could be used to develop novel oncology treatments.
news Blueprint for adapting US labs for COVID-19 diagnostic testing 13 May 2020 | By Victoria Rees (Drug Target Review) Researchers in Boston have repurposed their lab into a centre to test samples for COVID-19, releasing a blueprint of how to do so for other labs in the US.
news Free to use COVID-19 Protein Portal launched for researchers in UK 13 May 2020 | By Victoria Rees (Drug Target Review) The COVID-19 Protein Portal, established by UKRI and Wellcome, will allow scientists in the UK to access protein reagents needed for research.
whitepaper ebook: High-content analysis and infectious disease 12 May 2020 | By PerkinElmer Learn how you could use high-content analysis for functional & phenotypic assays in your infectious disease research or drug discovery.
news Procedure developed to create murine models of COVID-19 for testing of therapeutics and vaccines 12 May 2020 | By Victoria Rees (Drug Target Review) Russian researchers have created a process for the development of mouse models for use in pre-clinical studies of COVID-19 treatments and vaccines.
webinar Establishing Alpha CETSA HT in primary screening 7 May 2020 | By PerkinElmer High-throughput screening (HTS) cascades have evolved to ensure that high quality hits can be identified from large screening collections.
