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SARS-CoV-2 immunodominant epitopes identified as vaccine candidates

12 June 2020 | By Victoria Rees (Drug Target Review)

Researchers have analysed the SARS-CoV-2 proteome to reveal seven promising immunodominant epitopes that could aid in the development of a COVID-19 vaccine.

whitepaper

Whitepaper: Optimised homogenisation for virus studies

11 June 2020 | By Bertin Instruments

Best practices and optimised protocols with Precellys for high throughput sample preparation related to virus studies.

article

What immuno-oncology research can tell us about COVID-19

11 June 2020 | By Dr Jing Watnick (Vigeo Therapeutics)

Dr Jing Watnick discusses how lessons learnt from cancer immunotherapy treatments could be applied to the development of COVID-19 therapies.

surface of several coronavirus particles

news

Protease inhibitors could be highly effective against SARS-CoV-2

10 June 2020 | By Hannah Balfour (Drug Target Review)

Researchers reveal the main protease (Mpro) of SARS-CoV-2 is highly sensitive to disruption, therefore Mpro inhibitors could be a potential COVID-19 therapeutic.

lungs, diaphram and pleural space highlighted in red

news

Researchers develop a novel respiratory system simulator

10 June 2020 | By Hannah Balfour (Drug Target Review)

Scientists reveal their reliable and tuneable simulator created using swine lungs, synthetic actuators and artificial muscles.

video

Video: ESHG 2019 conference discussion panel: automated sample preparation

10 June 2020 | By Thermo Fisher Scientfic

A result is only as good as the sample preparation that preceded it.

video

Video: Overview of the KingFisher^TM instruments

10 June 2020 | By Thermo Fisher Scientific

ESHG 2019: Automated sample preparation using magnetic bead technology and KingFisher instruments.

news

Study identifies pathway responsible for blood-brain barrier impairment in Alzheimer’s

9 June 2020 | By Hannah Balfour (Drug Target Review)

The team found that the expression of the APOE4 gene variant in pericytes caused amyloid plaque formation in a blood-brain barrier model.

whitepaper

Application note: High-throughput pathogen detection using a novel MagMAX kit and OpenArray technology

9 June 2020 | By Thermo Fisher Scientfic

Automated detection and isolation of pathogens for multiple samples types.

video

Video: Isolate Circulating tumor cells using the KingFisher

9 June 2020 | By Thermo Fisher Scientfic

New opportunities for liquid biopsy: At automated workflow for isolating circulating tumor cells using KingFisher instruments.

viruses in orange surrounding blue neurons

news

Researchers find microglia are key to protecting brain from viral infection

8 June 2020 | By Hannah Balfour (Drug Target Review)

The team found microglia and CD8 T cells were vital to protecting neurons from vesicular stomatitis virus (VSV) infection and suggest loss of taste and smell in COVID-19 could be due to a certain mechanism of infection.

whitepaper

Application note: Sensitive detection of viral nucleic acids

8 June 2020 | By Thermo Fisher Scientific

A simple and sensitive method for nucleic acid extraction from virus-containing samples, with a range of viral loads.

whitepaper

Application note: Metagenomic analysis of the human microbiome

8 June 2020 | By Thermo Fisher Scientfic

Isolate high-quality, inhibitor-free DNA and RNA from human stool and other sample types suitable for metagenomics sequencing.

news

Researchers suggest animal experiments may be too standardised to be reproducible

5 June 2020 | By Hannah Balfour (Drug Target Review)

Experts suggest that increasing biological and conditional variations in their experiments could not only make them more reproducible but also reduce the total number of animals required.

article

TMPRSS2 inhibitors, Bromhexine, Aprotinin, Camostat and Nafamostat as potential treatments for COVID-19

4 June 2020 | By Arsalan Azimi (Shiraz University of Medical Sciences)

Arsalan Azimi explains why inhibiting TMPRSS2 with clinically proven protease blockers could work as a therapeutic strategy against COVID-19.

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