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Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
Flow cytometry is a common technique used to identify different immune cell types in mixed population samples such as peripheral blood or tissue samples.
When exosomes were first discovered they were thought to be nothing more than cellular waste containers, but it is now thought that the integral membrane proteins, soluble proteins, and nucleic acid contained within exosomes can be taken up by cells and influence their function.
Modern day oncology therapies have seen significant innovation in the last decade. It is high time we commit to using biomarkers that are driven by rational design and the latest computational methods.
The number of immuno-oncology active agents has seen a tremendous boost during the past three years. The 2019 global immuno-oncology pipeline consists of almost 3,900 agents, making immuno-oncology discovery very attractive.
Scientists have idenified that variation in a gene called Mucin 6 appears to indicate a tendency for acquiring Alzheimer’s disease.
Structural and functional study of the nervous system, also known as Neuroscience, is one of the scientific fields that has always crystallized the hopes and fantasy of humankind - not only interms of disease understanding and treatment but also in terms of capacity improvement.
Researchers discover that a non-coding region of the genome originates a key molecule for the proliferation of cancerous tumours.
An animal model to test HIV infection in infants could lead to biomarkers that predict viral rebound after ART interruption.
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
Researchers have discovered a non-coding RNA which could be used as a biomarker and in new therapies for prostate cancer.
For biomarker discovery efforts, primary cell assays, and patient-derived xenograft work, among others, access to fresh human surgical tissue is an essential component in obtaining reliable results.
A specific type of MRI, neuromelanin-sensitive magnetic resonance imaging, could lead to the measurement of a psychosis biomarker...
A blood test to measure pain has been developed, and could potentially aid physicians with more accuracy in diagnosis and prescriptions...
A biomarker that can differentiate between chronic cystitis (inflammation of the bladder) and a non-muscle invasive-type blood cancer could aid diagnosis...
Arginase 2 could be used as a drug target target to protect vision after optic nerve trauma, as removal of this enzyme decreases retinal neuron death...
