news
New biomarker identified for early diagnosis of lung cancer
High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.
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Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
news
CKAP4 biomarker identifies stage I lung cancer
Scientists in Japan have discovered a promising new biomarker – cytoskeleton-associated protein 4 (CKAP4) – for lung cancer, potentially transforming the way the disease is diagnosed and treated.
news
Study provides insight into blood signatures of inflammation
A new study has identified a pattern of inflammation associated with cardio-metabolic risks...
news
T cell populations in CLL patients indicate potential success of CAR-T cell therapy
Researchers have discovered the reason why some patients with advanced chronic lymphocytic leukaemia (CLL) don't respond to chimeric antigen receptor (CAR) T cell therapy...
news
Scientists find possible autism biomarker in cerebrospinal fluid
Researchers have found that low vasopressin in the cerebrospinal fluid may be a biomarker for autism...
webinar
Biomarker endpoints for Parkinson’s disease
26 April 2018 | By Charles River Laboratories
This webinar provides a comprehensive review of the validation data from established and novel animal models of Parkinson’s disease.
news
Blood test may predict future risk of cardiovascular events
A study of 27,000 women finds that branched-chain amino acid levels in the bloodstream are as predictive of heart disease as LDL cholesterol, other risk factors...
news
Biomarkers may help provide personalised treatment for brain cancer
Researchers in Brazil have identified seven biomarkers that could be used to indicate which glioma patients are likely to experience an aggressive form of the brain cancer.
article
How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
news
A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
news
Fragile X imaging study reveals differences in infant brains
For the first time, researchers have used MRIs to show that babies with the neurodevelopmental condition fragile X syndrome had less-developed white matter compared to infants that did not develop the condition...
news
Alzheimer’s patients exhibit changes in certain blood lipids typical of premature ageing
Research at MedUni Vienna’s Centre for Brain Research has investigated changes in certain lipids (choline phospholipids) in the plasma of elderly people who were healthy and those suffering from Alzheimer’s disease.
news
Tracking changes in circulating tumour cells shows promise for cancer screening
Researchers in the United States have developed improved methods for capturing circulating tumour cells (CTCs) on clinical samples, with a view to assessing treatment for cancer patients and screening for the disease.
article
Streamlining drug discovery assays for cancer and cardiovascular disease
Declining R&D productivity is a key challenge in the pharmaceutical industry. To increase the success rate of candidate drugs entering the clinical phase, companies must address the early stages of drug discovery.
news
Nanopore sensors used to detect molecular biomarkers for osteoarthritis
Scientists have been able to measure a specific molecule indicative of osteoarthritis and a number of other inflammatory diseases using a newly developed technology...
