news
Tongue microbiome could help to detect early-stage pancreatic cancer
The bacteria living in the tongue's microbiome could provide an insight into an individuals heath, and may help to detect pancreatic cancer earlier...
List view / Grid view
Biomarkers
Biomarkers are a naturally occurring molecule, gene, or characteristic by which a particular disease can be identified.
news
Ubiquilin-4 biomarker links cancer progression to genome instability
High level of specific protein in tumours indicates prognosis as well as optimal treatments...
news
Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
article
Expert view: High-throughput screening – make an impact by removing barriers
For drug discovery and biomarker research, screening campaigns are employed to identify potential new treatments for diseases and to answer questions that remain unknown in the scientific community.
article
Under the microscope: CROs and microplate reader requirements
Contract Research Organisations rely on microplate readers for effective hit discovery. Ian Waddell, of Charles River Laboratories, explains what his needs are.
news
Biomarkers may predict Zika-related birth defects
Researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus...
news
Biomarker discovered for heart failure with preserved ejection fraction
A biomarker has been discovered for the most common type of heart failure - heart failure with preserved ejection fraction...
news
Biomarkers to detect and prevent liver cancer
An increase in the expression of sugar-burning 'glycolytic' enzymes in precancerous cirrhotic livers has been identified and could be used as a biomarker...
news
Droplet Digital PCR detects and quantifies cancer mutation
Two ddPCR-based assays were developed to detect the two mutations in the promoter region of the TERT gene, which could be used as biomarkers...
news
Water as a biomarker against cancer?
The Tn antigen appears in around 90 percent of cancers, and its structure is greatly affected by the addition of water molecules...
news
CRISPR technique identifies Alzheimer’s biomarker
UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...
news
CT45 biomarker found in ovarian cancer can predict response to therapy
New approach could prolong survival and trigger an immune...
article
Metabolomics in drug and biomarker discovery
Metabolomics is the state-of-the-art qualitative or quantitative analysis of metabolites present in biological samples. Since the majority of diseases are associated with metabolic alterations – either as a cause or result of the disease process – metabolomics is increasingly being used in drug and biomarker discovery.
news
New biomarker panel could accelerate autism diagnoses
Researchers have identified a group of blood metabolites that could help detect some children with autism spectrum disorder (ASD)...
article
Expert view: Generate high‑content information using flow cytometry
Flow cytometry has become a widely used technology in life science research since its development in the 1970s. It is also essential for many biopharmaceutical and biotechnology companies due to its proficiency in identifying biomarkers, finding new inhibitory antibodies, and assessing the efficiency of new pharmacological protocols.
