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How bacteria behind hospital infections block out antibiotics revealed
Scientists have shown that drug-resistant bacteria infections shut out antibiotics by closing tiny doors in their cell walls.
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Antibiotics
Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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Anti-viral immune discovery could lead to improved vaccines
A molecular switch that impacts immune responses to viral infections has been identified which could lead to better strategies to develop vaccines.
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Synthetic molecules could provide new antibiotics
Using a novel technique, researchers have created new molecules effective at killing bacteria, providing new antibiotic drug targets.
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Novel technique reveals how TB antibiotics reach their targets
Researchers have used a new method to understand how antibiotics fight TB, which can guide future drug developments.
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Application note: Detection of anti-drug antibody (ADA) using single molecule counting (SMCTM) technology
All biological therapeutics have the potential to induce an immunemediated response ranging from benign to severe adverse effects.
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Gut microbiome directs immune system to fight cancer
The advent of immune checkpoint inhibitors is a major breakthrough in cancer immunotherapy...
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Book mechanism identified as communication method for bacterial toxins
Researchers have identified the mechanism by which highly toxic compounds communicate, and how they use vesicles to be transported...
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Simple mechanism that ensures bacterial resistance
The team used techniques used by physicists along with highly specialised equipment to investigate deep into the bacterial membrane...
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Peptide research gives insight on tackling bacteria
Researchers have paved the path towards redesigning antibiotics through the alteration of the peptide assembly involved in the process...
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Naturally occurring potent antibiotic revealed
A natural antibiotic was found to be made from an enzyme, through it triggering chemical reactions that help the production of the bacterial toxin...
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CRISPR repurposed to develop better antibiotics
Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
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Bacteria compete for ‘ownership’ of human tissue
Research has shown how the same species of bacteria compete for space on human tissue, with researchers saying the mechanism could be used in research...
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Repurposing wasp venom as antibiotic drugs
Researchers have used wasp venom to create variants of a peptide that is potent against bacteria but nontoxic to human cells...
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Prolonging antibiotic potency by differentiating between resilience and resistance
Distinguishing whether bacteria are resistant to antibiotics or resilient to them is hugely important in determining the success of the treatment...
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Supercoils in DNA could give insights to antibiotic drug development
DNA gyrase, a molecular machine used to prevent DNA from coiling, could be used to ensure bacterial DNA coils, reducing the risk of infection to humans...
