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Discovering the mechanisms of antibiotic resistance could lead to better drugs
A single change to the structure of bacterial ribosomes prevents macrolide antibiotics from binding and killing the bacteria, according to a study.
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Antibiotics
Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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CBD shown to kill Gram-negative bacteria in pre-clinical studies
Researchers have shown that CBD can kill Gram-negative bacteria, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.
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Scientists identify nutrient that helps prevent bacterial infection
Scientists have identified a potential alternative to antibiotics, a nutrient named taurine that helps the microbiome kill invading bacteria.
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Identification of novel biosynthetic pathways in lichens could lead to new therapeutics
Scientists have identified a new family of biosynthetic genes in lichens with unknown functions, which could produce new molecules for the pharmaceutical industry.
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Tetracycline antibiotics show promise against Zika virus
A new study shows that methacycline, a commonly used antibiotic, can reduce the neurological damage caused by Zika virus infections in mice.
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Simple molecule could combat antibiotic-resistant gonorrhoea and meningitis, study shows
An inexpensive molecule showed efficacy against antibiotic-resistant Neisseria gonorrhoeae and Neisseria meningitidis in an animal model.
![Wasp on a wooden platform [Credit: University of Pennsylvania].](https://drug.russellpublishing.co.uk/wp-content/uploads/Vespula-lewisii-wasp-750x500.jpg)
![Wasp on a wooden platform [Credit: University of Pennsylvania].](https://drug.russellpublishing.co.uk/wp-content/uploads/Vespula-lewisii-wasp-e1602594547599.jpg)
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Novel antimicrobial molecules derived from wasp venom
Altering the mastoparan-L (mast-L) peptide found in Vespula lewisii wasp venom, researchers created several novel antimicrobial molecules.
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Gramicidin A antibiotic analogues safe for human cells developed
A team has developed 10 new versions of the antibiotic gramicidin A, which they say should be safe for use in pills or injections.
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Platform for hit-to-lead identification of antibacterial lysins developed
A group of scientists has created a novel high-throughput hit-to-lead development platform to identify engineered antibacterial lysins.
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Novel compounds show efficacy against C. diff
Researchers have developed two novel trifluoromethylthio compounds which showed potent activity in protecting mice from Clostridioides difficile (C. diff) infection.
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Adding to the arsenal: targeting human proteins for controlling M. tuberculosis growth
The National Institute of Health envisions a plan for managing tuberculosis in the 21st century. Included in this proposal is targeting host proteins as an add-on therapy to antibiotics. Infectious disease biologists are focusing on this strategy and it is a topic of active research. Recently, a multinational research team…
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Novel lysin-based antibacterial agent could help combat MRSA
Researchers have engineered F12, a lysin-based antibacterial drug, to have limited negative side-effects and so it can be administered repeatedly without loss of efficacy.
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Researchers discover a novel class of antibiotics for urinary tract infections
Researchers reveal their antibiotics disrupt the bacterial TonB system which uropathogenic E. coli (UPEC) uses to uptake iron in order to cause urinary tract infections.
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Beautyberry leaf could be the secret to combatting MRSA infections
A compound extracted from the leaf of the American beautyberry re-sensitised methicillin-resistant Staphylococcus aureus (MRSA) to beta-lactam antibiotics.
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Approach to produce antibiotic compounds from actinobacteria developed
Researchers have created a method to promote the production of new antibiotic or antiparasitic compounds from the genomes of actinobacteria.
