whitepaper Product hub: High-throughput screening of cyclic peptide libraries for developing drugs to challenging targets 28 September 2021 | By BMG Labtech GmbH Professor Christian Heinis explains how peptides could offer the next generation of therapeutics and what is required to screen libraries of cyclic peptides.
news Promising new avenue to tackle obesity-related diabetes 2 July 2021 | By Mandy Parrett (Drug Target Review) New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.
news Researchers make key discovery involved in re-engineering of peptides 11 May 2021 | By Victoria Rees (Drug Target Review) A team has characterised a key part of the peptide synthesis process, showing that only the main building block needs to be changed for re-engineering.
news Computational method used to quantify tRNAs in any organism 1 March 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a new technique called mim-tRNAseq to measure, map and analyse tRNAs in cells, providing insight into disease.
news Synthetic peptides block atherosclerosis in pre-clinical studies 15 February 2021 | By Victoria Rees (Drug Target Review) Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
news D-serine could protect against epileptic seizures 15 October 2020 | By Hannah Balfour (Drug Target Review) Scientist identified the mechanism through which temporal lobe epileptic seizures are sparked and that D-serine can interfere with this process, preventing seizures.
news Protease inhibitors could be highly effective against SARS-CoV-2 10 June 2020 | By Hannah Balfour (Drug Target Review) Researchers reveal the main protease (Mpro) of SARS-CoV-2 is highly sensitive to disruption, therefore Mpro inhibitors could be a potential COVID-19 therapeutic.
news Flow synthesis technology enables faster protein production 1 June 2020 | By Hannah Balfour (Drug Target Review) The novel protocol allows proteins over 100 amino acids long to be synthesised in hours and include amino acids that do not occur in the human proteome.
news Human enzymes could be driving COVID-19 evolution, suggest researchers 21 May 2020 | By Hannah Balfour (Drug Target Review) Post-infection genome editing could be the cause of mutations in the SARS-CoV-2 virus responsible for the COVID-19 pandemic, driving its evolution.
news Investigational drug kills pancreatic cells in mice by cutting off cysteine supply 3 April 2020 | By Victoria Rees (Drug Target Review) Researchers have demonstrated that cysteinase, a new drug compound, can starve pancreatic cells of cysteine supply, causing ferroptosis.
news Artificial binding protein could be developed into a novel anti-viral or cancer therapy 18 March 2020 | By Hannah Balfour (Drug Target Review) Scientists have created an artificial protein able to recognise and bind cell surface carbohydrates with high affinity and selectivity.
news L-serine could be used to treat ALS, after promising results in primate study 24 February 2020 | By Hannah Balfour (Drug Target Review) Researchers have shown that, when treated with L-serine, a non-human primate model of ALS had fewer pathologies associated with the disease.
news 3D tissue models of brain tumours created in brain-mimicking environment 11 October 2019 | By Rachael Harper (Drug Target Review) A new platform has the potential to better understand what dictates the invasive behaviour of brain tumours.
news New method for developing medical imaging tracers discovered 21 June 2019 | By Drug Target Review A new medical imaging tracing method has been discovered by scientists which can better track drugs in the body.
news Anti-inflammatory bacterial protein discovered in zebrafish 8 November 2018 | By Iqra Farooq (Drug Target Review) An anti-inflammatory bacterial protein discovered in zebrafish could lead to the discovery of anti-inflammatory proteins within humans...
