William Tansey

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Targeting the HCF-1 protein causes cancerous cells to self-destruct

Disrupting the interaction between the MYC oncogene and its co-factor,…

1 February 2021 | By Hannah Balfour (Drug Target Review)

Disrupting the interaction between the MYC oncogene and its co-factor, host cell factor (HCF)–1, was sufficient to cause Burkitt’s lymphoma cells to self-destruct in vivo.

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William Tansey

Targeting the HCF-1 protein causes cancerous cells to self-destruct