Professor Michele Vendruscolo

Three-dimensional (3D) illustration of amyloid beta plaques (brown mesh-like shapes) forming between neurons and disrupting their function. Amyloid plaques are a hallmark of Alzheimer’s Disease.

news

Developing drugs for disordered proteins

Scientists have developed a drug-like molecule to target amyloid-beta, a…

6 November 2020 | By Hannah Balfour (Drug Target Review)

Scientists have developed a drug-like molecule to target amyloid-beta, a disordered protein implicated in Alzheimer's disease that has been considered undruggable.

neurons in purple surrounded by yellow protein aggregates - idea of Alzheimer's disease

news

Antibody for amyloid beta oligomers could revolutionise Alzheimer’s field

Scientists have designed a high affinity antibody for pathogenic amyloid…

27 May 2020 | By Hannah Balfour (Drug Target Review)

Scientists have designed a high affinity antibody for pathogenic amyloid beta oligomers, a key driver of Alzheimer’s disease, for use in further research and as a potential diagnostic tool.

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Professor Michele Vendruscolo

Developing drugs for disordered proteins

Antibody for amyloid beta oligomers could revolutionise Alzheimer’s field