Professor Juan Perilla

A coiling protein 'shell,' called a nucleocapsid, shown here, surrounds Ebola's genetic material, which consists of single-strand RNA. University of Delaware researchers are simulating the way molecules of this nucleocapsid move and interact, atom by atom, to understand their functions and expose targets for anti-viral treatments [Credit: Juan Perilla Laboratory].

news

The nucleocapsid as a novel drug target for Ebola virus

Using supercomputer stimulations researchers reveal that the structural stability of…

22 October 2020 | By Hannah Balfour (Drug Target Review)

Using supercomputer stimulations researchers reveal that the structural stability of the Ebola nucleocapsid is depended on the presence of RNA and interactions with charged ions.

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Professor Juan Perilla

The nucleocapsid as a novel drug target for Ebola virus