Dr Sophie Zimmermann

Structure based drug discovery facilitated by crystallography

Drugs exert therapeutically meaningful effects if they bind with appropriate…

15 September 2017 | By Dr Sheraz Gul, Dr Sophie Zimmermann

Drugs exert therapeutically meaningful effects if they bind with appropriate selectively and potency to their respective targets. Although many of the assay techniques employed in early-stage drug discovery provide evidence that a drug is acting upon the target under investigation, this is often indirect and the site of action and…