news Researchers identify RNA molecule that suppresses prostate tumours 8 November 2021 | By Anna Begley (Drug Target Review) Scientists discover a long noncoding RNA, termed NXTAR, and a small molecule drug that could be used to treat prostate cancer.
news Defective proteins found to be potential targets for Alzheimer’s treatments 12 July 2021 | By Anna Begley (Drug Target Review) US researchers have identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that could be used against these targets.
news Natural killer cell immunotherapy shows promise against melanoma 30 June 2021 | By Victoria Rees (Drug Target Review) Researchers have shown that natural killer cell immunotherapy effectively treated mice harbouring human melanoma tumours.
news Dual antibodies effective against SARS-CoV-2 variants in animal study 22 June 2021 | By Victoria Rees (Drug Target Review) In mice and hamsters, therapies made from two antibodies were found to be mostly effective against a range of SARS-CoV-2 variants.
news Tiny implant cures diabetes in mice without triggering immune response 7 June 2021 | By Victoria Rees (Drug Target Review) Scientists have developed an implant that releases insulin-secreting cells which has shown success at treating diabetes in mice.
news SARS-CoV-2 mAb cocktail effective against all known variants of virus 8 March 2021 | By Victoria Rees (Drug Target Review) A monoclonal antibody (mAb) cocktail, that targets sites on the Spike protein other than the E484K residue, can neutralise SARS-CoV-2.
news Researchers identify mutations in single genes that lead to cerebral palsy 1 October 2020 | By Victoria Rees (Drug Target Review) A new study has shown that the mutated FBXO31 and RHOB genes can each alone cause cerebral palsy, offering potential drug targets.
news COVID-19 vaccine elicits high levels of neutralising antibodies in mice 17 August 2020 | By Victoria Rees (Drug Target Review) A potential COVID-19 vaccine, made from a modified vesicular stomatitis virus with the SARS-CoV-2 Spike protein, was shown to protect mice against the virus.
news Induced pluripotent stem cells and CRISPR reversed diabetes in mice 23 April 2020 | By Victoria Rees (Drug Target Review) Induced pluripotent stem cells made to produce insulin and CRISPR, used to correct a genetic defect, cured Wolfram syndrome in mice.
news Early natural killer cells more effective than adult versions, find researchers 24 March 2020 | By Victoria Rees (Drug Target Review) Researchers have shown that natural killer (NK) cells work best as an immunotherapy when in an early stage of development, so could be manufactured from pluripotent stem cells.
news Boosting natural killer cells in mice with eczema relieves condition 28 February 2020 | By Victoria Rees (Drug Target Review) Researchers have found that using IL-15 to boost natural killer cell numbers in mice helps to combat eczema and could be a therapeutic strategy for patients.
news Genes linked to cell survival during sepsis identified 22 July 2019 | By Victoria Rees (Drug Target Review) Researchers have found a set of genes which helps cells survive during sepsis in mice and could inform potential treatments for the condition.
news Boosting immune cells could provide TB treatment 28 June 2019 | By Drug Target Review A new study has identified a class of immune cells that respond to tuberculosis, indicating a drug target for the condition.
news Immune cells could be key to tuberculosis treatment, study finds 7 June 2019 | By Victoria Rees (Drug Target Review) Researchers have found that certain immune cells aid in fighting tuberculosis bacteria, providing a new drug target.
news Study shows that immune cells determine growth of certain tumours 4 June 2019 | By Drug Target Review A new study shows that the growth rate of a tumour does not depend solely on how quickly the cancer cells can divide.
