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Cartilage growth gene TRPV4 shows promise for joint repair therapy

26 August 2021 | By Anna Begley (Drug Target Review)

The discovery that the TRPV4 gene regulates cartilage growth could lead to treatments for osteoarthritis and other cartilage diseases.

GABA possible treatment avenue of type 2 diabetes

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Promising new avenue to tackle obesity-related diabetes

2 July 2021 | By Mandy Parrett (Drug Target Review)

New findings from collaborative research in the United States have identified a promising new treatment avenue for type 2 diabetes patients centring on the activity of the amino acid, GABA.

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Alliance to create atlas of human genetic variants launched

6 April 2021 | By Victoria Rees (Drug Target Review)

The Atlas of Variant Effects Alliance will develop a map of human genetic variants to advance the understanding and treatment of disease.

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Antibodies from recovered COVID-19 patients inhibit SARS-CoV-2 infection in cells

28 September 2020 | By Victoria Rees (Drug Target Review)

Pre-clinical studies in cells and hamsters have shown that potent antibodies from COVID-19 patients can prevent infection from SARS-CoV-2.

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MaveDB: database to aid research into genetic causes of disease

5 November 2019 | By Drug Target Review

Researchers in Australia and the US have launched the first open-source database detailing genetic variants that impact human health and disease.

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New antiviral drug demonstrated to effectively treat influenza in models

25 October 2019 | By Rachael Harper (Drug Target Review)

A new antiviral drug has been reported in a study that researchers believe has high clinical potential as a next-generation influenza drug.

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Human stem cell combination could help damaged hearts live longer

6 August 2019 | By Rachael Harper (Drug Target Review)

A combination of heart cells derived from human stem cells could lead to developing a treatment for heart failure.

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Psoriasis treated with compound derived from immune cells

19 April 2018 | By Dr Zara Kassam (Drug Target Review)

A compound may be effective against other autoimmune diseases, mouse study shows...

news

BNIP1 identified as a risk gene for ALS

10 April 2018 | By Dr Zara Kassam (Drug Target Review)

Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...

news

PARK14 protein associated with inflammation in Parkinson’s

15 March 2018 | By Dr Zara Kassam (Drug Target Review)

Study overturns previous ideas about enzyme linked to many illnesses

news

A potential new target for scratching out itch

20 July 2016 | By Victoria White, Digital Content Producer

Scientists have discovered how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord...

news

Making immunotherapy more effective in treating pancreatic cancer

4 July 2016 | By Victoria White, Digital Content Producer

Scientists have shown that immunotherapy against pancreatic cancer can be effective when given alongside drugs that break up the fibrous tissue in tumours...

news

Mouse models show how Zika migrates into the placenta

11 May 2016 | By Victoria White, Digital Content Producer

In the models, the Zika virus was observed migrating from the bloodstream into the placenta, where it multiplied...

news

Electron microscopy details infection mechanisms of coronaviruses

29 February 2016 | By Victoria White

High-resolution cryo-electron microscopy and supercomputing have now made it possible to analyse in detail the infection mechanisms of coronaviruses...

news

TAxI holds promise as a carrier for spinal cord treatments

17 February 2016 | By Victoria White

The small peptide has been shown to be an effective at shuttling functional proteins into the spinal cord after a muscle injection...

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