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AI technology to screen existing drugs for use against COVID-19

2 April 2020 | By Victoria Rees (Drug Target Review)

A collaboration aims to utilise a compound library of 15,000 clinically-ready molecules and screen then against three COVID-19 targets.

news

TEX264 protein could be targeted to help protect DNA from damage

9 March 2020 | By Hannah Balfour (Drug Target Review)

Scientists have identified that the TEX264 protein and associated enzymes protect the genome from damage, which could lead to new anti-ageing and neurodegeneration therapies.

someone holding chest having a suspected heart attack

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Macrophages could be the target of novel heart attack therapies

3 February 2020 | By Hannah Balfour (Drug Target Review)

Research determined macrophages’ role in forming a permanent cardiac scar after a heart attack, the researchers suggest altering this behaviour may make the scar temporary and allow restoration of heart function.

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Sir Peter Ratcliffe awarded joint Nobel Prize for Physiology or Medicine

8 October 2019 | By Victoria Rees (Drug Target Review)

The researcher Sir Peter Ratcliffe and two others have been jointly awarded the Nobel Prize for Physiology or Medicine 2019.

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Protective antibodies identified that could be key to malaria vaccine

18 June 2019 | By Drug Target Review

A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.

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A universal flu vaccine may be in sight

21 September 2018 | By Iqra Farooq (Drug Target Review)

Researchers from Oxford have identified the initial steps on the path towards creating a universal influenza vaccine that could last for life...

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Computational analysis identifies a new clinical phenotype of severe malaria

4 September 2018 | By Drug Target Review

Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...

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Novel imaging biomarker to help predict coronary inflammation

29 August 2018 | By Drug Target Review

Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality...

news

Injected VEGF-C could prevent heart failure

12 July 2018 | By Drug Target Review

Vascular Endothelial Growth Factor C (VEGF-C) could aid the repair and recovery of hearts after a heart attack, by enabling immune cells to clear dead and dying cells...

news

Lipid accumulation in the brain may be an early sign of Parkinson’s disease

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

A collaborative team of researchers has found that elevated levels of certain types of lipids in the brain may be an early sign of Parkinson's...

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Genetic catalyst identifies the evolution of antibiotic resistance

26 April 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria...

news

Organ-on-chip technology tests for hepatitis B virus

16 February 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have become the first in the world to test how pathogens interact with artificial human organs...

news

Inhibiting β-lactamase may reverse antibiotic resistance

23 October 2017 | By Dr Zara Kassam (Drug Target Review)

By developing a chemical to inhibit β-lactamase enzymes, a significant proportion of antibiotic resistance may successfully be reversed...

news

Genome editing reveals a role for OCT4 in human embryogenesis

21 September 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development...

news

New synthetic polio vaccine candidate

15 August 2017 | By Dr Zara Kassam (Drug Target Review)

A collaborative team of scientists have developed a novel synthetic vaccine with a method grown in plants that uses virus-like particles...

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