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Drug sponge could minimise effects of cancer therapy
A drug 'sponge' could be the future method of soaking up excess drugs within the body after cancer treatments such as chemotherapy to prevent side effects...
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North Carolina University
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PAINS management: an open source model to eliminate nuisance compounds
High-throughput screening (HTS) technologies have enabled the routine testing of millions of compounds towards the identification of novel ‘hit’ molecules for therapeutic targets. Oftentimes in this drug discovery process, however, compounds that show promising activity in primary screens show no activity during subsequent hit qualification or progression efforts.
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miR-31 may help target treatments for Crohn’s patients
Researchers have pinpointed a single molecule - microRNA-31 (miR-31) - the levels of which predict whether a patient has subtype 1 or subtype 2 of Crohn's disease...
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AI system designs drugs from scratch
An artificial-intelligence approach created can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates...
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Cell types underlying schizophrenia identified
Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...
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XBP-1 pathway plays key role in CF airway inflammation
13 January 2016 | By Victoria White
Researchers have discovered that the XBP-1 pathway was implicated in the hyper-inflammatory response of cystic fibrosis alveolar macrophages...
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Researchers identify two biomarkers linked to severe atherosclerosis
7 July 2015 | By Victoria White
Researchers have created a first-of-its-kind animal model to pinpoint two biomarkers that are elevated in the most severe form atherosclerosis...
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Smart insulin patch could make painful injections a thing of the past for diabetes sufferers
23 June 2015 | By Victoria White
Researchers have created the first smart insulin patch that can detect increases in blood sugar levels and secrete doses of insulin into the bloodstream...