news New approach for treating cystic fibrosis shows success in mice 17 June 2021 | By Victoria Rees (Drug Target Review) Researchers have developed a potential strategy to treat cystic fibrosis, using oligonucleotides to correct certain gene defects.
news EIDD-2801 proven to prevent SARS-CoV-2 infection in vivo 10 February 2021 | By Victoria Rees (Drug Target Review) The drug EIDD-2801 was shown to prevent SARS-CoV-2 replication and infection of cells in a new mouse model containing human lung tissue.
news Activating STING enhances CAR T-cell activity in solid tumours, shows study 4 January 2021 | By Hannah Balfour (Drug Target Review) Researchers were able to eradicate breast cancer in mice when they combined CAR T cells with STING pathway agonists and immunotherapeutic antibodies.
news Mapping SARS-CoV-2 infection in the airway 2 June 2020 | By Hannah Balfour (Drug Target Review) Researchers found there is a gradient of SARS-CoV-2 infectivity down the airway and that the severe pneumonia symptoms may be caused by aspiration of oral contents into the lungs.