news First lab-grown mini-thyroids produced from patients’ own tissue 15 March 2021 | By Victoria Rees (Drug Target Review) Thyroid mini-organs have been generated in the lab by researchers, which are able to self-renew and differentiate into functional tissue.
news Revealed protein structure could aid in Huntington’s disease treatment development 15 February 2021 | By Victoria Rees (Drug Target Review) Using NMR spectroscopy, researchers have partially observed the structure of heat shock proteins that bind to proteins that cause Huntington's disease.
news RNA structures of SARS-CoV-2 reveal potential drug targets 11 November 2020 | By Victoria Rees (Drug Target Review) The SARS-CoV-2 RNA genome structure has been studied by researchers who identified several potential drug targets.
news Novel tuberculosis transport protein could be target of new treatments 1 April 2020 | By Hannah Balfour (Drug Target Review) Cryogenic electron microscopy revealed that the vitamin B12 transporter on Mycobacterium tuberculosis acts like a non-selective sluice, transporting both the vitamin and antibiotics.
news Blocking bacterial competence could prevent antibiotic resistance 4 March 2020 | By Hannah Balfour (Drug Target Review) Scientists suggest competence-blocking, ‘anti-evolution’ drugs could be administered alongside antibiotics to prolong the period before bacterial resistance emerges.
news Molecular motors used to develop bone marrow-derived mesenchymal stem cells 29 January 2020 | By Victoria Rees (Drug Target Review) Researchers have used molecular motors powered by UV light to control the growth of bone marrow-derived mesenchymal stem cells.
news Key mechanism in tuberculosis survival discovered 19 August 2019 | By Victoria Rees (Drug Target Review) A new study has revealed that M. tuberculosis uses a unique type of antacid which gives immune cells indigestion, enabling the bacteria to survive.
news Cancer cell nutrient pathway mechanism discovered 1 August 2019 | By Victoria Rees (Drug Target Review) Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
news How gut bacteria affect the treatment of Parkinson’s disease 21 January 2019 | By Dr Zara Kassam (Drug Target Review) Researchers have investigated the ability of gut microbiota to influence the bioavailability of levodopa, a drug used in the treatment of Parkinson's...
news Scientists decode ASCT2 protein as possible cancer drug target 7 June 2018 | By Drug Target Review Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.