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New algorithm could make CRISPR gene editing more precise

11 June 2021 | By Victoria Rees (Drug Target Review)

Researchers have created an algorithm that can predict the efficiencies of guide RNAs for CRISPR, potentially making it more precise.

news

Cannabinoids could reduce essential tremors in patients

22 March 2021 | By Victoria Rees (Drug Target Review)

A synthetic cannabinoid has shown promise as a treatment for involuntary tremors by activating astrocytes in mouse models.

news

Researchers develop novel way to identify new cancer drugs

26 January 2021 | By Victoria Rees (Drug Target Review)

A team has developed a new way to discover peptide therapeutics that inhibit HDAC enzymes and are effective against cancer.

news

Researchers reveal protein function that could improve chemotherapy

18 December 2020 | By Victoria Rees (Drug Target Review)

Scientists have found that the RFWD3 protein could play a role in recruiting DNA key repair and signalling factors, impacting chemotherapy.

news

New insulin molecule can self-regulate blood sugar in rats

4 December 2020 | By Victoria Rees (Drug Target Review)

Researchers have developed a novel insulin molecule that responds to glucose levels in the blood sugar of rats, which they say could help patients with type 1 diabetes.

EEG waves indicating an epileptic seizure overlaid with a brain

news

Single-nucleus transcriptomics reveals novel epilepsy targets

8 October 2020 | By Hannah Balfour (Drug Target Review)

Study reveals which neurons are most affected by epilepsy, presenting novel targets for seizure drug discovery and development.

white or blue bacteria colonies speckling petri dish agar

news

CRISPR discovery could be used to combat multi-drug resistant bacteria

25 March 2020 | By Victoria Rees (Drug Target Review)

A study has shown that plasmids use type IV CRISPR-Cas against competing plasmids, leading the researchers to suggest the method as a novel way to tackle multi-drug resistant bacteria.

Potential of widely used drug could be unlocked with new method

news

New mass spec technique used to determine structure of sugars

25 March 2020 | By Rachael Harper (Drug Target Review)

A new method has been invented that boosts the mapping of heparan sulfates and which the researchers say could be widely used for drug discovery.

news

New compound could alleviate side effects of antidepressant drugs

23 March 2020 | By Victoria Rees (Drug Target Review)

Researchers have revealed a new substance that can bind well to serotonin transporters, offering a potential way to lessen the side effects of antidepressant therapies.

news

Researchers identify novel signalling systems in cells

1 November 2019 | By Victoria Rees (Drug Target Review)

A study has revealed five new signalling processes in GPCR receptors on cells that have high therapeutic potential.

news

Researchers reveal how body repairs damaged DNA

28 October 2019 | By Victoria Rees (Drug Target Review)

A team has imaged the process that the body uses to stabilise DNA, which could be used to develop therapies for conditions such as cancer.

news

Researchers identify bacteria defence system mechanism

26 September 2019 | By Victoria Rees (Drug Target Review)

The process that bacteria use to defend themselves has been revealed by researchers, who also demonstrated how to activate the process.

news

New study shows insight into how cells maintain their identity

23 September 2019 | By Rachael Harper (Drug Target Review)

A new study shows the ways in which epigenetic mechanisms control the activity of genes and may have an impact on the future treatment of certain cancers.

news

Oxygen sensitive nanoparticles used for 3D printing of complex tissue-like structures

2 October 2018 | By Drug Target Review

Researchers have implemented oxygen sensitive nanoparticles into a gel material that can be used for 3D printing of complex, biofilm and tissue-like structures...

news

Sugar specific molecules show promising results for new allergy vaccine

27 September 2018 | By Drug Target Review

Using sugar molecules researchers have developed a new vaccine for hay fever that may reduce treatment times and increase the effectiveness of treatments...

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