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Strep A vaccine target identified for global use
Researchers use high-throughput DNA sequencing technology to identify a potential vaccine target for Strep A.
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University of Cambridge
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Novel drug discovery approach for personalised mental health treatment
Researchers have developed a method that could drastically accelerate the search for new drugs to treat mental health disorders.
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Mitochondrial diseases could be treated with gene therapy
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
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Potential indicator for the early detection of dementias
A team of neuropathologists worked together to show that the impairments affecting mitochondria also affect neighbouring organelles...
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Targeting BAFF reduces the development of atherosclerosis
The researchers identified that BAFF to have anti-inflammatory properties, which has a positive effect on plaque size and atherosclerosis...
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Artificial gene defect reveals target to fight genetic disease
Scientists have deployed a novel genetic screen to search for synthetic viable interactions on special lines of Fanconi Anaemia-defective cells...
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Scientists create ‘genetic atlas’ of proteins in human blood
Researchers have created the first detailed genetic map of human proteins...
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Leukaemia protective role of Y chromosome gene discovered
Scientists have discovered the first leukaemia protective gene that is specific to the male-only Y chromosome...
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Inhibiting NAT10 provides therapeutic target for HGPS
Scientists have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford progeria syndrome...
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Scientists discover promising off-switch for inflammation
Scientists have discovered that itaconate - a molecule derived from glucose - acts as a powerful off-switch for macrophages...
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Neural stem cell treatment may offer relief for MS
Scientists have shown that skin cells re-programmed into brain stem cells, transplanted into the central nervous system, help reduce inflammation and may be able to help repair damage caused by MS...
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Calcium may play a role in the development of Parkinson’s
Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease...
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New insights into alpha-synuclein function holds promise for Parkinson’s treatment
Researchers have gained important insights into the role of alpha-synuclein – the protein associated with Parkinson’s disease – in nerve cells and how calcium affects its function. This knowledge is hoped to better arm scientists regarding future treatment for the disease.
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Mitochondrial disease can be inherited from healthy parents
Researchers have shown for the first time how children can inherit a severe -- potentially fatal - mitochondrial disease from a healthy mother...
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Inhibiting METTL3 destroys AML cells without harming normal blood cells
An unexpected drug target for acute myeloid leukaemia could open new avenues to develop effective treatments against the potentially lethal disease...
