news Brain organoids used to identify promising treatments for Rett syndrome 10 December 2020 | By Hannah Balfour (Drug Target Review) Two drugs, Nefiracetam and PHA 543613, were able to return neuronal signalling to near normal in organoids derived from patients with the autism spectrum disorder, Rett syndrome.
news Could FDA-approved drug heparin prevent SARS-CoV-2 infection? 17 September 2020 | By Hannah Balfour (Drug Target Review) SARS-CoV-2 entry into human cells is dependent on heparan sulfate and disrupting this interaction using heparin reduces infectivity of the coronavirus, find scientists.
news iPSC-derived natural killer cells show promise against leukaemia in mice 16 June 2020 | By Victoria Rees (Drug Target Review) By deleting the CISH gene from natural killer cells made from iPSCs, researchers say they have effectively treated leukaemia in vivo and in vitro.
news Gene therapy could cure Danon disease, life-threatening genetic condition 19 March 2020 | By Hannah Balfour (Drug Target Review) Researchers have shown a gene therapy to correct the genetic mutation that causes Danon disease is successful in pre-clinical trials.
article Exploring future spinal cord injury therapies 11 March 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores five of the latest research developments in the field of spinal cord injury (SCI) repair.
news Gut organoid helped to define leaky gut and could aid in treatment development 11 February 2020 | By Hannah Balfour (Drug Target Review) Research has shown that leaky gut, the break down of gut lining junctions, could be targeted to reduce inflammation using metformin using an organoid model.
