news European patent upheld for foundational CRISPR-Cas9 intellectual property 18 February 2020 | By Victoria Rees (Drug Target Review) Arguments filed in opposition to a patent for foundation CRISPR-Cas9 intellectual property have been broadly rejected by the European Patents Office.
news Antiviral treatments lead to development of a new kind of cancer drug 24 January 2020 | By Rachael Harper (Drug Target Review) Drugs that were being developed to treat enterovirus have also been found to treat certain cancers in mice.
news Mutant form of Ebola could be used in vaccine development 17 September 2019 | By Victoria Rees (Drug Target Review) A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.
news Cause of MS damage in the brain identified 18 July 2019 | By Victoria Rees (Drug Target Review) A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.
news ‘CRISPR babies’ may have shorter life expectancy 6 June 2019 | By Drug Target Review A study of almost half a million people links a mutation that protects against HIV infection to an earlier death.
news Female animals should be included in trials, new argument proposes 3 June 2019 | By Victoria Rees (Drug Target Review) Using exclusively male animals in experiments biases results, argues Rebecca Shansky.
news New avenues open for the treatment of thrombosis 28 May 2019 | By Drug Target Review New study describes for the first time the structure of Ixolaris and its action on the inhibition of thrombus formation.
news CRISPR-Chip enables digital detection of DNA without amplification 26 March 2019 | By Drug Target Review Researchers have found multiple applications for the CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) gene editing technology since it came into use by the scientific community...
news CRISPR repurposed to develop better antibiotics 14 January 2019 | By Iqra Farooq (Drug Target Review) Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
news Ebola-fighting protein found in the human body 13 December 2018 | By Drug Target Review A study has found that the human protein, RBBP6, helps fight Ebola virus by interfering with the virus replication cycle…
news Disrupting serotonin receptors to control spread of dengue and Zika 18 October 2018 | By Drug Target Review Researchers are developing methos to decrease the body size and weight of mosquitoes in order to control the spread of dengue and Zika...
news Bacterial outer membranes may be key to new antibiotics 22 July 2018 | By Drug Target Review The outer membrane surrounding the cell wall of bacteria may be a key target for approaches to a new form of antibacterial drugs...
news Artificial gene defect reveals target to fight genetic disease 13 June 2018 | By Drug Target Review Scientists have deployed a novel genetic screen to search for synthetic viable interactions on special lines of Fanconi Anaemia-defective cells...
news DNMT3A crystal structure linked to cancer development 12 February 2018 | By Drug Target Review Scientists offer important information for understanding de novo DNA methlylation...
news Immune system found to protect against MRSA infections 7 February 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus...