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European patent upheld for foundational CRISPR-Cas9 intellectual property

18 February 2020 | By Victoria Rees (Drug Target Review)

Arguments filed in opposition to a patent for foundation CRISPR-Cas9 intellectual property have been broadly rejected by the European Patents Office.

Antiviral treatments lead to development of a new kind of cancer drug

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Antiviral treatments lead to development of a new kind of cancer drug

24 January 2020 | By Rachael Harper (Drug Target Review)

Drugs that were being developed to treat enterovirus have also been found to treat certain cancers in mice.

news

Mutant form of Ebola could be used in vaccine development

17 September 2019 | By Victoria Rees (Drug Target Review)

A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.

news

Cause of MS damage in the brain identified

18 July 2019 | By Victoria Rees (Drug Target Review)

A study has discovered that the damage of projection neurons in the brain is caused by immune cells, leading to MS.

news

‘CRISPR babies’ may have shorter life expectancy

6 June 2019 | By Drug Target Review

A study of almost half a million people links a mutation that protects against HIV infection to an earlier death.

news

Female animals should be included in trials, new argument proposes

3 June 2019 | By Victoria Rees (Drug Target Review)

Using exclusively male animals in experiments biases results, argues Rebecca Shansky.

news

New avenues open for the treatment of thrombosis

28 May 2019 | By Drug Target Review

New study describes for the first time the structure of Ixolaris and its action on the inhibition of thrombus formation.

news

CRISPR-Chip enables digital detection of DNA without amplification

26 March 2019 | By Drug Target Review

Researchers have found multiple applications for the CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) gene editing technology since it came into use by the scientific community...

news

CRISPR repurposed to develop better antibiotics

14 January 2019 | By Iqra Farooq (Drug Target Review)

Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...

news

Ebola-fighting protein found in the human body

13 December 2018 | By Drug Target Review

A study has found that the human protein, RBBP6, helps fight Ebola virus by interfering with the virus replication cycle…

news

Disrupting serotonin receptors to control spread of dengue and Zika

18 October 2018 | By Drug Target Review

Researchers are developing methos to decrease the body size and weight of mosquitoes in order to control the spread of dengue and Zika...

news

Bacterial outer membranes may be key to new antibiotics

22 July 2018 | By Drug Target Review

The outer membrane surrounding the cell wall of bacteria may be a key target for approaches to a new form of antibacterial drugs...

news

Artificial gene defect reveals target to fight genetic disease

13 June 2018 | By Drug Target Review

Scientists have deployed a novel genetic screen to search for synthetic viable interactions on special lines of Fanconi Anaemia-defective cells...

news

DNMT3A crystal structure linked to cancer development

12 February 2018 | By Drug Target Review

Scientists offer important information for understanding de novo DNA methlylation...

news

Immune system found to protect against MRSA infections

7 February 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus...

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