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University of Bath

Parkinson's Disease dopamine neuron with alpha-synuclein Lewy Body inside

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Novel alpha-synuclein structures could be the target for future Parkinson’s therapies

24 August 2020 | By Hannah Balfour (Drug Target Review)

Researchers observed new structures of alpha-synuclein aggregates in their study exploring how the presence of cell membrane phospholipids impacts protein aggregation.

news

DIRC3 tumour suppressor could be a new target for melanoma therapies

16 January 2020 | By Hannah Balfour (Drug Target Review)

A study has shown that long non-coding RNA called DIRC3 can block melanoma growth and could be used to identify new targets for skin cancer therapies.

article

The challenges of hit-to-lead in drug discovery

7 October 2019 | By Victoria Rees (Drug Target Review)

A study that identified 12 novel compounds that may prove valuable against new drug targets for leishmaniasis and Chagas disease was not without complication. Here, we discuss the findings but also the challenges the researchers reported in their hit-to-lead study.

news

High-throughput method used to identify cancer drug candidates

25 September 2019 | By Victoria Rees (Drug Target Review)

A study using high-throughput screening has revealed some promising compounds that could be used in future cancer treatments.

news

Scientists screen molecules for new prostate cancer drugs

14 May 2018 | By Drug Target Review

Cancer researchers have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers...

news

Non-coding RNA helps suppress breast cancer

2 February 2016 | By Victoria White

A team of scientists from Bath, Cambridge and the USA has identified a piece of non-coding RNA that stops cells turning cancerous...

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Recommended

University of Bath

Novel alpha-synuclein structures could be the target for future Parkinson’s therapies

DIRC3 tumour suppressor could be a new target for melanoma therapies

The challenges of hit-to-lead in drug discovery

High-throughput method used to identify cancer drug candidates

Scientists screen molecules for new prostate cancer drugs

Non-coding RNA helps suppress breast cancer