news Study reveals novel targets for treating atopic dermatitis 12 January 2021 | By Hannah Balfour (Drug Target Review) Understanding how Staphylococcus aureus bacteria colonises skin affected by atopic dermatitis could lead to new treatments that help prevent the spread of antibiotic resistance, say scientists.
news New gene therapy could treat dominant optic atrophy 27 November 2020 | By Victoria Rees (Drug Target Review) Researchers have found that an OPA1-targeted gene therapy can treat dominant optic atrophy in pre-clinical trials.
news Researchers dicover novel targets for rheumatoid arthritis therapies 13 November 2020 | By Hannah Balfour (Drug Target Review) Researchers have identified that autoreactive B cells and a protein that enables them to invade joints could be promising drug targets for the most common inflammatory arthritis.
news Toll-like receptor could be targeted to treat age-related macular degeneration 24 February 2020 | By Hannah Balfour (Drug Target Review) Scientists have implicated toll-like receptor 2 (TLR2) in age-related macular degeneration and shown that knocking it out can improve symptoms in animal models.
news Blocking IL-17 could provide new multiple sclerosis treatment strategy 6 February 2020 | By Victoria Rees (Drug Target Review) Researchers have revealed that inhibiting IL-17 could prevent the effects of autoimmune diseases, including multiple sclerosis.
news Inflammatory regulatory protein identified by researchers 22 November 2019 | By Victoria Rees (Drug Target Review) A study has discovered that the PKM2 protein plays a role in regulating immune cells and blocking this could be a potential treatment for inflammatory diseases.
news New biological targets could lead to therapies for drug-resistant cancers 11 September 2019 | By Rachael Harper (Drug Target Review) A study on how Polycombs regulate cellular identity could lead to alternative treatments for patients with drug-resistant cancer.
news Motor neuron disease electrical signalling pathways mapped 1 August 2019 | By Victoria Rees (Drug Target Review) A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
news Scientists uncover how HIV evades elimination by the immune system 20 April 2018 | By Drug Target Review A team of scientists from Trinity College Dublin has identified the mechanism that enables HIV to evade the immune system, paving the way for a new curative treatment.
news Presence of protein aggregates as important as form in cell death 19 November 2015 | By Victoria White Scientists have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue...
