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CCT245737 boosts the effectiveness of chemotherapy
23 July 2015 | By Victoria White
CCT245737, a new drug that blocks cancer’s escape route from chemotherapy, could be used to treat deadly lung and pancreatic cancers...
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The Institute of Cancer Research (ICR)
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Scientists use cryo-EM to image one of the central proteins of life
2 July 2015 | By Victoria White
Scientists have pioneered the use electron cryo-microscopy (cryo-EM) to picture in exquisite detail one of the central proteins of life...
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Mutated TCF12 gene linked to aggressive form of brain cancer
12 June 2015 | By Victoria White
Scientists have identified that errors in a gene known as TCF12 are associated with more aggressive forms of a disease called anaplastic oligodendroglioma...
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Dormant cancer cells can ‘wake up’ after decades
28 May 2015 | By Victoria White
Researchers have found genetic evidence that dormant cancer cells can avoid the effects of treatment only to ‘wake up’ many years later...
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Scientists unveil ‘Rosetta Stone’ of prostate cancer
21 May 2015 | By Victoria White
Almost 90% of men with advanced prostate cancer carry genetic mutations in their tumours that could be targeted by either existing or new cancer drugs...
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ROCK inhibitors could stop the spread of melanoma cells
6 May 2015 | By Victoria White
Scientists at The Institute of Cancer Research have found that ROCK inhibitors dramatically reduced the ability of melanoma cells to move through tissue...
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Trial shows benefit of ‘BRCA-targeting’ drug, olaparib, in prostate cancer
21 April 2015 | By Victoria White
Men with prostate cancer benefit from treatment with the pioneering drug olaparib according to the results of a major trial presented today...
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Consortium signs deal with Basilea to develop resistance-busting cancer drugs
1 April 2015 | By Victoria White
A consortium will collaborate with Basilea to progress a new family of cancer drugs designed to block several key cancer-causing proteins at once...
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New role uncovered for ‘oldest’ tumour suppressor gene- the retinoblastoma gene
26 March 2015 | By Victoria White
Scientists have revealed a brand new function for one of the first cancer genes ever discovered – the retinoblastoma gene...
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Detecting prostate tumour cells in blood can give an early warning of treatment failure
23 March 2015 | By Victoria White
A blood test that measures the number of prostate tumour cells shed into the bloodstream can act as an early warning sign that treatment is not working...
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PARP inhibitors could work in larger group of patients
19 March 2015 | By Victoria White
PARP inhibitors that target cancers with mutations in the BRCA breast cancer genes could also work against tumours with another type of genetic fault...
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‘Stem cell’ test could identify most aggressive breast cancers
4 March 2015 | By The Institute of Cancer Research
Testing breast cancer cells for how closely they resemble stem cells could identify women with the most aggressive disease, a new study suggests...
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Manipulating cells’ shapes could treat breast cancer
4 March 2015 | By The Institute of Cancer Research
Changing the shape of breast cancer cells could make the disease more sensitive to treatments – even driving the body’s own inflammatory response against a tumour – a new study shows...
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New breast cancer test links immune ‘hotspots’ to better survival
27 February 2015 | By The Institute of Cancer Research
Scientists have developed a new test which can predict the survival chances of women with breast cancer by analysing images of ‘hotspots’ where there has been a fierce immune reaction to a tumour...
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Cancer risk linked to DNA ‘wormholes’
19 February 2015 | By The Institute of Cancer Research
Single-letter genetic variations within parts of the genome once dismissed as ‘junk DNA’ can increase cancer risk through wormhole-like effects on far-off genes, new research shows...