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Behavioural screen in C. elegans reveals Parkinson’s drug candidates

24 February 2021 | By Victoria Rees (Drug Target Review)

Researchers have developed a workflow to study the behaviour of C. elegans in a high-throughput screen to identify Parkinson's disease drugs.

Red blobs (indicating T cells) surrounding and touching larger white blobs (acting as cancer cells) - idea of T cell therapy for cancer

news

New ‘smart’ cell therapies show promise in solid tumours

27 November 2020 | By Hannah Balfour (Drug Target Review)

By combining machine learning and T-cell engineering researchers were able to develop cell therapies that can selectively and effectively target and destroy solid tumours.

news

Proteins vital for hepatitis B infection discovered by researchers

10 March 2020 | By Victoria Rees (Drug Target Review)

A new study has revealed five factors and proteins that hepatitis B infection needs for replication of its DNA, providing insight into the disease.

news

Cell division recreated in a test tube demonstrates TPX2 protein role in cancer

21 January 2020 | By Hannah Balfour (Drug Target Review)

Studies have identified that the TPX2 protein recruits the molecular machinery required for the branching microtubule nucleation process, so could be a target for cancer therapies.

news

Triple-negative breast cancer could be treated using experimental treatment

4 January 2019 | By Drug Target Review

A mouse study has revealed that triple-negative breast cancer could be tackled by using recombinant Tinagl1 in therapy targeting signalling pathways...

news

Vaccine signatures point to a better understanding of infectious diseases

29 November 2018 | By Drug Target Review

Researchers have developed a comprehensive way to evaluate how immune responses of humanised mice measure up to actual humans...

news

Researchers apply computing power to track the spread of cancer

2 July 2018 | By Drug Target Review

Researchers have developed a new computational method that increases the ability to track the spread of cancer cells from one part of the body to another...

news

Macrophages support mammary stem cells via chemical signalling

21 May 2018 | By Drug Target Review

An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...

news

Study uncovers molecular events that reveal pathway toward heart disease therapy

14 February 2018 | By Drug Target Review

Scientists from UNC-Chapel Hill and Princeton University in the United States, reveal key molecular details that hold promise for ultimate goal of heart disease reversal.

news

Cell culture system could offer cancer breakthrough

31 August 2017 | By Dr Zara Kassam (Drug Target Review)

A new cell culture system that provides a tool for preclinical cancer drug development and screening has been developed...

news

Global vaccine-development fund could save thousands of lives

4 August 2015 | By Victoria White

For vaccine development, financial barriers persist: pharma companies see high costs with limited market potential, and government support is lacking...

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