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Novel CAR T-cell therapy could help cure HIV

1 September 2020 | By Hannah Balfour (Drug Target Review)

The designers of the Dual Chimeric Antigen Receptor (CAR) T cell therapy report it slows HIV replication and leads to a smaller viral reservoir in HIV-infected mice.

news

CRISPR ‘minigene’ used to prevent genetic liver disease in mice

13 February 2020 | By Victoria Rees (Drug Target Review)

Researchers have developed a new CRISPR technique, using a minigene, which was inserted into mouse DNA, resulting in improved liver disease symptoms.

news

Study paves way for new vaccines to protect infants against infections

9 January 2020 | By Rachael Harper (Drug Target Review)

An mRNA vaccine has been developed which has elicited strong immune responses in mice in the presence of maternal antibodies.

news

Gene therapy for DMD safely preserves muscle function

8 October 2019 | By Rachael Harper (Drug Target Review)

Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.

news

CAR T-cell therapy could be harnessed to treat heart disease

11 September 2019 | By Rachael Harper (Drug Target Review)

New study finds immunotherapy reduces cardiac fibrosis and restores heart function in mice after cardiac injury.

news

Mouse models’ mimic lung disease

20 August 2018 | By Drug Target Review

Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...

news

T cell populations in CLL patients indicate potential success of CAR-T cell therapy

3 May 2018 | By Drug Target Review

Researchers have discovered the reason why some patients with advanced chronic lymphocytic leukaemia (CLL) don't respond to chimeric antigen receptor (CAR) T cell therapy...

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Recommended

Penn Medicine

Novel CAR T-cell therapy could help cure HIV

CRISPR ‘minigene’ used to prevent genetic liver disease in mice

Study paves way for new vaccines to protect infants against infections

Gene therapy for DMD safely preserves muscle function

CAR T-cell therapy could be harnessed to treat heart disease

Mouse models’ mimic lung disease

T cell populations in CLL patients indicate potential success of CAR-T cell therapy