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Novel CAR T-cell therapy could help cure HIV
The designers of the Dual Chimeric Antigen Receptor (CAR) T cell therapy report it slows HIV replication and leads to a smaller viral reservoir in HIV-infected mice.
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Penn Medicine
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CRISPR ‘minigene’ used to prevent genetic liver disease in mice
Researchers have developed a new CRISPR technique, using a minigene, which was inserted into mouse DNA, resulting in improved liver disease symptoms.
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Study paves way for new vaccines to protect infants against infections
An mRNA vaccine has been developed which has elicited strong immune responses in mice in the presence of maternal antibodies.
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Gene therapy for DMD safely preserves muscle function
Gene therapy for the treatment of Duchenne muscular dystrophy has safely stopped the muscle deterioration associated with the disease.
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CAR T-cell therapy could be harnessed to treat heart disease
New study finds immunotherapy reduces cardiac fibrosis and restores heart function in mice after cardiac injury.
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Mouse models’ mimic lung disease
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
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T cell populations in CLL patients indicate potential success of CAR-T cell therapy
Researchers have discovered the reason why some patients with advanced chronic lymphocytic leukaemia (CLL) don't respond to chimeric antigen receptor (CAR) T cell therapy...
