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4 February 2016 | By Victoria White
Compounds that produce elevated levels of TTP in humans may offer an effective treatment for inflammatory diseases, such as rheumatoid arthritis and multiple sclerosis...
20 January 2016 | By Victoria White
The collaboration will focus on identifying ligands for NR2F6 using Regen's screening methodology and the expertise and unique chemical libraries of NCATS...
4 January 2016 | By Victoria White
BPN14770 may be a possible treatment for dementia and Alzheimer’s disease with less potential for side effects than rolipram...
22 December 2015 | By Victoria White
A study suggests that enhancing proteasome activity with drugs during the early stages of Alzheimer’s may prevent dementia and reduce damage to the brain...
16 November 2015 | By Victoria White
Investigators found that a protein called SIRT3 provides resistance to obesity-related inflammatory response...
10 November 2015 | By Victoria White
Scientists from the University of New Mexico and NIH have created a cholesterol-lowering vaccine that leads to reductions in LDL cholesterol in mice and macaques...
14 October 2015 | By Victoria White
Research has shown that gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa...
6 October 2015 | By Victoria White
Researchers have found that they can use gene therapy to improve visual in mice models for the vision disorder Leber hereditary optic neuropathy (LHON)...
In much the same way that kinases and phosphatases attach and remove phosphate groups from proteins to modulate their activity, there are a series of enzymes (E1, E2, E3) that add one or more ubiquitins onto a protein, as well as enzymes that remove them (deubiquitinases; DUBs), thereby regulating their…
20 August 2015 | By Victoria White
Scientists have reported that an experimental vaccine given six weeks before exposure to MERS-CoV fully protects rhesus macaques from disease...
17 August 2015 | By Victoria White
Researchers supported by the NIH have discovered a type of cell, known as hybrid hepatocytes, essential to regeneration of the liver...
29 July 2015 | By Victoria White
A two-step regimen of experimental vaccines against Middle East respiratory syndrome (MERS) prompted immune responses in mice and rhesus macaques...
27 July 2015 | By Victoria White
Researchers have discovered RGS2, a protein being looked at as a target for hypertension and heart ailments, plays a vital role in healthy egg-sperm union...
22 July 2015 | By Victoria White
NIAID researchers have devised a way to induce protective immunity in mice against a wide array of influenza viruses using a VLP vaccine...
20 July 2015 | By Victoria White
Lower levels of cholesterol in certain immune cells may help explain why some HIV-infected people are able to naturally control disease progression...
