news New drug target identified for myelodysplastic syndrome 8 October 2021 | By Anna Begley (Drug Target Review) Researchers have uncovered how mutations affecting RNA splicing alter cells to develop myelodysplastic syndrome (MDS).
news Researchers discover class of drugs that could treat mantle cell lymphoma 23 June 2021 | By Victoria Rees (Drug Target Review) A screening campaign has revealed that small molecule inhibitors of the SOX 11 oncogene are toxic to mantle cell lymphoma in vitro.
news Inexpensive drug protects against COVID-19 inflammation in pre-clinical trials 31 March 2021 | By Victoria Rees (Drug Target Review) A drug called topotecan (TPT) was administered to mice up to four days after COVID-19 infection, reducing inflammation and morbidity.
news SARS-CoV-2 specific antibodies persist for five months in mild cases 30 October 2020 | By Hannah Balfour (Drug Target Review) In a study of mild-to-moderate COVID-19 patients scientists established that the level of certain antibodies remained stable for five months.
news Two biomarkers of COVID-19 disease survival identified by researchers 25 August 2020 | By Victoria Rees (Drug Target Review) Scientists have revealed that the cytokines IL-6 and TNF-α are two biomarkers of inflammation that can predict the severity of COVID-19.
news Macrophages identified as drug target for serous cavity cancers 6 April 2020 | By Victoria Rees (Drug Target Review) The loss of RXR function, a molecular mechanism which determines the identity macrophages, has been revealed as a drug target for cancers in serous cavities.
news Researchers identify target to improve dendritic cell ability to fight tumours 31 March 2020 | By Victoria Rees (Drug Target Review) A new study has shown that the role of T cell-suppressing dendritic cells can be reversed in mice, indicating that immunotherapies could be improved with this method.
