news Researchers achieve DNA methylation removal in mouse models 9 November 2021 | By Anna Begley (Drug Target Review) The study showed that DNA “de-methylation” activity can be targeted to anywhere in the DNA and may be a new therapeutic strategy.
news Scientists uncover mechanisms of potential COVID-19 drug targets 28 September 2021 | By Anna Begley (Drug Target Review) Researchers have used CRISPR and cryogenic electron microscopy to unravel the workings of two receptors involved in diseases such as cancer and COVID-19.
news Researchers discover process viruses use to block antiviral immune response 16 February 2021 | By Victoria Rees (Drug Target Review) A team has revealed that viruses ‘hijack’ a molecular process in the cell, inhibiting the body’s response to viral infection.
news Researchers link cellular transport pathway to glioblastoma 18 January 2021 | By Victoria Rees (Drug Target Review) A study has said that restoring a particular protein's activity could be a new therapeutic strategy to treat glioblastoma.
article Five developments in oncology targets 30 July 2020 | By Hannah Balfour (Drug Target Review) Drug Target Review explores some of the newest oncologic drug targets, including those for glioblastoma, lung cancer and breast cancer.
news Effective analgesics are ‘some way away’ due to bias in pain research, says researcher 26 May 2020 | By Hannah Balfour (Drug Target Review) A review of pain research suggests it is biased towards males, despite most chronic pain sufferers being female, resulting in ineffective analgesics.
news Researchers reveal structure of mega-enzymes from bacteria and fungi 1 May 2020 | By Victoria Rees (Drug Target Review) Researchers have uncovered the structure of nonribosomal peptide synthetases (NRPSs), an important ingredient in drug production.
news Research focus should remain on high quality studies during COVID-19 pandemic, say scientists 24 April 2020 | By Victoria Rees (Drug Target Review) Exceptions to high quality research should not be made simply because of the COVID-19 pandemic, argue scientists in a new commentary.
article The latest developments in diabetes drug discovery 30 March 2020 | By Victoria Rees (Drug Target Review) Several new advances have been made in the field of drug discovery for diabetes – here, three of the most recent have been rounded up.
news Study identifies virulence factors of Leishmania 13 August 2019 | By Drug Target Review Researchers have discovered the mechanism behind the spread of Leishmania, indicating a potential drug target.
article Stem Cell In-Depth Focus 2019 5 June 2019 | By Drug Target Review This in-depth focus looks at the modification of stem cells to facilitate their efficient delivery to tumours, highlighting the new development of pluripotent stem cells.
news DNA nanostructures for drug delivery remain a technical challenge 13 May 2019 | By Drug Target Review Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are 'flawed'.
news Drug candidate offers hope of vocal improvement for ADNP syndrome 16 November 2018 | By Drug Target Review Scientists have uncovered a promising drug candidate that appears to normalise the vocal communication mechanism deficiencies experienced in genetic disorder ADNP.
news AI algorithm accurately predicts Alzheimer’s disease onset 5 October 2018 | By Drug Target Review Scientists have developed an algorithm that can more accurately predict cognitive decline that leads to Alzheimer’s disease. Early preventive measures may help delay and even halt the disease’s onset.
news ATP1A3 gene mutations associated with infantile forms of schizophrenia 21 June 2018 | By Dr Zara Kassam (Drug Target Review) Scientists have identified novel genes associated with a specific form of schizophrenia the discovery will aid diagnosis and development of treatments...
