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La Jolla Institute for Immunology (LJI)

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$2.6 million granted to create pan-coronavirus vaccine

25 October 2021 | By Anna Begley (Drug Target Review)

The La Jolla Institute for Immunology and Brigham and Women's Hospital will collaborate to develop a pan-coronavirus vaccine.

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T-cell exhaustion may limit long-term immunity in COVID-19 patients

22 January 2021 | By Hannah Balfour (Drug Target Review)

Researchers suggest patients who develop mild COVID-19 may not be able to fight reinfection very effectively because their CD8+ T cells show signs of exhaustion.

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Researchers emphasise importance of antigen valency for vaccine efficacy

28 August 2020 | By Victoria Rees (Drug Target Review)

Researchers have shown that factoring in valency to vaccine design can improve the number of antibody binding sites on an antigen.

glowing yellow pancreas and red and blue blood wessels in the anatomy of a human

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Researchers halt type 1 diabetes onset by denervating the pancreas

27 August 2020 | By Hannah Balfour (Drug Target Review)

Scientists denervated the pancreas using surgery or pharmacological agents to protect it from immune-mediated beta cell destruction, preventing the onset of type 1 diabetes.

news

Potential target to control T follicular helper cells identified

23 June 2020 | By Victoria Rees (Drug Target Review)

A new study shows how the Bcl6 protein can regulate T follicular helper cells, presenting a target for autoimmune and infectious diseases.

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Recommended

La Jolla Institute for Immunology (LJI)

$2.6 million granted to create pan-coronavirus vaccine

T-cell exhaustion may limit long-term immunity in COVID-19 patients

Researchers emphasise importance of antigen valency for vaccine efficacy

Researchers halt type 1 diabetes onset by denervating the pancreas

Potential target to control T follicular helper cells identified