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Institute for Research in Biomedicine (IRB Barcelona)

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Bioactivity information of one million molecules compiled

1 July 2021 | By Victoria Rees (Drug Target Review)

Using deep machine learning, researchers have completed the activity profiles, from chemistry to clinical level, for one million molecules.

stem cell culture stored in liquid nitrogen

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Regulating cell plasticity through CDK8 inhibition

29 September 2020 | By Hannah Balfour (Drug Target Review)

Researchers show CDK8 inhibition reduces cell plasticity without damaging cells and suggest their approach could have implications for autoimmunity and oncology.

news

Researchers identify over 550 cancer-driving genes

20 August 2020 | By Victoria Rees (Drug Target Review)

Computational analysis has been used by researchers to examine 66 types of cancer and identify 568 genes that drive tumour development.

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Genes responsible for gender differences in tumours identified

19 August 2019 | By Rachael Harper (Drug Target Review)

A new study has identified possible regulators that determine differences in cancer tumours between genders.

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Study shows p38 protein regulates formation of new blood vessels

18 July 2019 | By Drug Target Review

A new study shows that the activity of p38 is important in MSCs, which can localise around blood vessels.

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Scientists achieve the first stable simulations of DNA crystals

21 January 2019 | By Drug Target Review

A study by researchers at the Institute for Research in Biomedicine has been the first to achieve stable simulations of DNA crystals...

news

EXD2 enzyme identified as key player in mitochondrial protein synthesis

19 January 2018 | By Drug Target Review

A team of researchers led by IRB Barcelona in Spain have identified a key function of the enzyme EXD2 as being the maintenance of protein production in the mitochondria.

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Discovery into cells’ energy supply could lead to targeted cancer treatment

16 January 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have made a significant breakthrough in understanding how the molecular machines that produce key proteins are cleaned and maintained.  ..

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Institute for Research in Biomedicine (IRB Barcelona)