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Study of liver cancer reveals MAGEA3 gene as new drug target
A study has shown that blocking the gene expression of MAGEA3 in liver cancer cells prevents the tumour from proliferating.
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Icahn School of Medicine at Mount Sinai.
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Airway-on-a-chip technology enables COVID-19 drug repurposing
An airway-on-a-chip has been used to show that amodiaquine inhibits SARS-CoV-2 infection, making it a potential COVID-19 therapeutic.
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Hepatitis C drugs shown to boost remdesivir’s activity against SARS-CoV-2
Four hepatitis C drugs have demonstrated promise as boosters to increase the efficacy of remdesivir against SARS-CoV-2 by as much as tenfold.
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CRISPR used to model acute myeloid leukaemia progression
CRISPR-Cas9 and stem cell technologies have been used to create a cellular model of acute myeloid leukaemia, revealing therapeutic targets.
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Exploring future spinal cord injury therapies
Drug Target Review explores five of the latest research developments in the field of spinal cord injury (SCI) repair.
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Researchers develop imaging technique to study 3D-printed brain tumours
A new method has been created by researchers to 3D bioprint tumours and image glioblastomas for the study of therapeutics.
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Multi-omics approach yields novel insight for peanut allergies
Researchers in New York have identified novel genes associated with the severity of peanut allergies and noted how these genes interact with other genes during allergic reactions. The findings could lead to better treatments for peanut allergies.
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‘Reverse vaccinology’ used to create novel HIV treatment
Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.
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Integrated multi-‘omic’ studies could lead to precision treatment for asthma
Researchers say integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients.
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New study brings universal flu vaccine a step closer
An international team of researchers has proven that targeting a specific area of the flu virus protects humans.
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Over 400 genes associated with schizophrenia identified
Researchers have identified new genes associated with schizophrenia and pinpointed the areas of the brain in which abnormal expression might occur...
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Drug targets for Dengue, Zika and Ebola viruses
US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…
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Critical cancer immunity genes identified using genetic barcoding
Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...
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Researchers identify new arthritis severity gene
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by...
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Three new genes linked to Alzheimer’s identified
An international research team has identified three new genes linked to the risk of Alzheimer’s disease...
