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Icahn School of Medicine at Mount Sinai.

news

Study of liver cancer reveals MAGEA3 gene as new drug target

25 June 2021 | By Victoria Rees (Drug Target Review)

A study has shown that blocking the gene expression of MAGEA3 in liver cancer cells prevents the tumour from proliferating.

article

Airway-on-a-chip technology enables COVID-19 drug repurposing

7 May 2021 | By Victoria Rees (Drug Target Review)

An airway-on-a-chip has been used to show that amodiaquine inhibits SARS-CoV-2 infection, making it a potential COVID-19 therapeutic.

news

Hepatitis C drugs shown to boost remdesivir’s activity against SARS-CoV-2

28 April 2021 | By Victoria Rees (Drug Target Review)

Four hepatitis C drugs have demonstrated promise as boosters to increase the efficacy of remdesivir against SARS-CoV-2 by as much as tenfold.

news

CRISPR used to model acute myeloid leukaemia progression

11 February 2021 | By Victoria Rees (Drug Target Review)

CRISPR-Cas9 and stem cell technologies have been used to create a cellular model of acute myeloid leukaemia, revealing therapeutic targets.

MRI scans showing a spinal cord injury in the thoracic region getting worse with time

article

Exploring future spinal cord injury therapies

11 March 2020 | By Hannah Balfour (Drug Target Review)

Drug Target Review explores five of the latest research developments in the field of spinal cord injury (SCI) repair.

news

Researchers develop imaging technique to study 3D-printed brain tumours

9 March 2020 | By Victoria Rees (Drug Target Review)

A new method has been created by researchers to 3D bioprint tumours and image glioblastomas for the study of therapeutics.

news

Multi-omics approach yields novel insight for peanut allergies

17 December 2019 | By Drug Target Review

Researchers in New York have identified novel genes associated with the severity of peanut allergies and noted how these genes interact with other genes during allergic reactions. The findings could lead to better treatments for peanut allergies.

news

‘Reverse vaccinology’ used to create novel HIV treatment

24 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have developed a new HIV vaccine which has shown success in monkeys in pre-clinical trial studies.

news

Integrated multi-‘omic’ studies could lead to precision treatment for asthma

3 July 2019 | By Drug Target Review

Researchers say integrated multi-'omic' studies could accelerate the use of precision medicine for asthma patients.

news

New study brings universal flu vaccine a step closer

4 June 2019 | By Drug Target Review

An international team of researchers has proven that targeting a specific area of the flu virus protects humans.

news

Over 400 genes associated with schizophrenia identified

26 March 2019 | By Drug Target Review

Researchers have identified new genes associated with schizophrenia and pinpointed the areas of the brain in which abnormal expression might occur...

news

Drug targets for Dengue, Zika and Ebola viruses

14 December 2018 | By Drug Target Review

US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…

news

Critical cancer immunity genes identified using genetic barcoding

22 October 2018 | By Iqra Farooq (Drug Target Review)

Genetic barcoding using Pro-codes and CRISPR could be used to identify critical cancer immunity genes to aid future therapeutics...

news

Researchers identify new arthritis severity gene

26 July 2018 | By Dr Zara Kassam (Drug Target Review)

A new gene associated with disease severity in models of rheumatoid arthritis has been identified by...

news

Three new genes linked to Alzheimer’s identified

24 May 2018 | By Drug Target Review

An international research team has identified three new genes linked to the risk of Alzheimer’s disease...

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Icahn School of Medicine at Mount Sinai.