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Novel database could accelerate drug repurposing for various diseases
NICEdrug.ch is an open-access database that may help scientists assess potential drugs for a range of diseases more quickly.
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Ecole Polytechnique Fédérale De Lausanne (EPFL)
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Researchers identify promising drug target for Huntington’s disease
Researchers have found the TBK1 enzyme regulates the degradation and clearance of the huntingtin protein, making it a drug target for Huntington's disease.
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Researchers develop first synthetic inhibitor of coagulation factor XII
A new FXII inhibitor has been developed that efficiently blocked coagulation in a thrombosis model without increasing the risk of bleeding.
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Researchers use algorithm to design articifical proteins for vaccines
Scientists have developed a method for designing artificial proteins that tell the immune system which antibodies to produce so could enhance vaccine design.
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Novel antiviral material made from sugar developed by researchers
Modified sugar molecules have been developed by researchers as antiviral materials which are non-toxic to humans, according to a new study.
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Super-resolution microscopy builds multicolour 3D images from 2D
Researchers have developed a method of exploiting fluorescence in microscopy to generate 3D images of organelles and structures within cells from 2D images...
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New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
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Democratising clinical genomics while protecting data privacy
Sophia Genetics co-founder and CEO, Jurgi Camblong, tackles issues of privacy and security for healthcare patient data...
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Blocking LRH-1 causes liver cancer cells to starve
13 June 2016 | By Victoria White, Digital Content Producer
Scientists at EPFL have found a way to starve liver cancer cells by blocking a protein that is required for glutamine breakdown - LRH-1...
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Reprogramming corrupted immune cells to attack tumours
13 June 2016 | By Victoria White, Digital Content Producer
Researchers at EPFL have found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumour...
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Implant turns the immune system against Alzheimer’s disease
17 March 2016 | By Victoria White
Scientists have developed a capsule containing cells that have been genetically engineered to produce antibodies against the Abeta...