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Ecole Polytechnique Fédérale De Lausanne (EPFL)

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Novel database could accelerate drug repurposing for various diseases

4 August 2021 | By Anna Begley (Drug Target Review)

NICEdrug.ch is an open-access database that may help scientists assess potential drugs for a range of diseases more quickly.

news

Researchers identify promising drug target for Huntington’s disease

6 August 2020 | By Victoria Rees (Drug Target Review)

Researchers have found the TBK1 enzyme regulates the degradation and clearance of the huntingtin protein, making it a drug target for Huntington's disease.

news

Researchers develop first synthetic inhibitor of coagulation factor XII

5 August 2020 | By Victoria Rees (Drug Target Review)

A new FXII inhibitor has been developed that efficiently blocked coagulation in a thrombosis model without increasing the risk of bleeding.

news

Researchers use algorithm to design articifical proteins for vaccines

20 May 2020 | By Victoria Rees (Drug Target Review)

Scientists have developed a method for designing artificial proteins that tell the immune system which antibodies to produce so could enhance vaccine design.

news

Novel antiviral material made from sugar developed by researchers

31 January 2020 | By Victoria Rees (Drug Target Review)

Modified sugar molecules have been developed by researchers as antiviral materials which are non-toxic to humans, according to a new study.

news

Super-resolution microscopy builds multicolour 3D images from 2D

1 October 2018 | By Iqra Farooq (Drug Target Review)

Researchers have developed a method of exploiting fluorescence in microscopy to generate 3D images of organelles and structures within cells from 2D images...

news

New ligand binding site identified through computer simulations

30 July 2018 | By Drug Target Review

Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...

article

Democratising clinical genomics while protecting data privacy

1 February 2017 | By Jurgi Camblong (CEO: Sophia Genetics)

Sophia Genetics co-founder and CEO, Jurgi Camblong, tackles issues of privacy and security for healthcare patient data...

news

Blocking LRH-1 causes liver cancer cells to starve

13 June 2016 | By Victoria White, Digital Content Producer

Scientists at EPFL have found a way to starve liver cancer cells by blocking a protein that is required for glutamine breakdown - LRH-1...

news

Reprogramming corrupted immune cells to attack tumours

13 June 2016 | By Victoria White, Digital Content Producer

Researchers at EPFL have found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumour...

news

Implant turns the immune system against Alzheimer’s disease

17 March 2016 | By Victoria White

Scientists have developed a capsule containing cells that have been genetically engineered to produce antibodies against the Abeta...

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Ecole Polytechnique Fédérale De Lausanne (EPFL)