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Ecole Polytechnique Fédérale De Lausanne

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Cyclisation reaction enables screening of macrocyclic compounds libraries

22 August 2019 | By Rachael Harper (Drug Target Review)

Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.

news

Double-bridged peptides bind any disease target

1 May 2018 | By Drug Target Review

Researchers have developed a new peptide format that they call double-bridged peptides...

news

Disrupting macrophage action aids melanoma immunotherapy success

13 April 2018 | By Drug Target Review

Scientists in Switzerland have uncovered a potential means of increasing effective treatment of melanomas with immunotherapy, by disrupting the action of macrophages.

news

Researchers uncover the origins of leprosy and reason for its drug resistance

25 January 2018 | By Drug Target Review

Scientists in Switzerland have developed the tools to sequence genes from the leprosy bacterium, Mycobacterium leprae, revealing information about its origins and reasons behind its resistance to drugs.

news

Alzheimer’s Tau protein forms toxic complexes with cell membranes

22 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers identify the sequence and structural factors that drive Tau interaction with membranes...

news

Metabolism can be used to subtype hepatoblastoma

18 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma...

news

New method developed for 3-D imaging

6 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have developed a microscopy method that generates fast and reliable 3D images of curvilinear structures...

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Recommended

Ecole Polytechnique Fédérale De Lausanne

Cyclisation reaction enables screening of macrocyclic compounds libraries

Double-bridged peptides bind any disease target

Disrupting macrophage action aids melanoma immunotherapy success

Researchers uncover the origins of leprosy and reason for its drug resistance

Alzheimer’s Tau protein forms toxic complexes with cell membranes

Metabolism can be used to subtype hepatoblastoma

New method developed for 3-D imaging