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Potential COVID-19 antiviral formulated with siRNA-nanoparticles

19 May 2021 | By Victoria Rees (Drug Target Review)

Scientists have created an antiviral therapy using lipid nanoparticles that deliver siRNA to the lungs to treat COVID-19 in mice.

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SARS-CoV-2 triggers antibodies from previous coronavirus infections

22 January 2021 | By Victoria Rees (Drug Target Review)

A new study has shown that previous coronavirus infection may contribute to the immune response of patients infected with SARS-CoV-2.

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Cancer-killing virus could improve precision medicine

2 December 2020 | By Victoria Rees (Drug Target Review)

A new cancer-killing virus called CF33 has shown success in pre-clinical trials, helping the immune system to eradicate tumours.

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Two small molecules revealed to combat mouse tumour growth in multiple cancers

17 June 2020 | By Victoria Rees (Drug Target Review)

Small molecules named CS1 (bisantrene) and CS2 (brequinar) have been developed by researchers to suppress the growth of tumours and have shown promise in mouse models.

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CAR T-cell receptors based on scorpion venom show efficacy in mice

5 March 2020 | By Victoria Rees (Drug Target Review)

Combining the chlorotoxin peptide with conventional CAR structures, researchers have created a new CAR T cell therapy that has successfully combatted glioblastomas in mice.

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Modified CRISPR gene editing tool could improve therapies

12 November 2019 | By Rachael Harper (Drug Target Review)

New cell experiments show more effective genetic 'cuts' that could one day become the foundation of more effective gene therapies.

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Novel CAR T-cell therapy for leukaemia and lymphoma

26 September 2019 | By Drug Target Review

Scientists in the US have developed a promising new CAR T-cell therapy that targets the BAFF-R protein, which has demonstrated superior cancer destruction to existing FDA-approved CAR-T therapies.

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New stem cell model to test treatments for neurodegenerative disorders

2 August 2018 | By Drug Target Review

The team found that astrocytes inhibit growth of precursor cells that become myelin, and speed up the neural network in the brain...

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